Results 111 to 120 of about 17,994,923 (296)

A Literature Review of Complementary and Alternative Medicine Used Among Diabetes Mellitus Patients [PDF]

, 2019
Diabetes is a chronic disease that requires regular and sustainable health management that involves proper treatment. Some diabetic patients use CAM, as well as conventional medicine, to maintain their health and control their blood sugar.
Agil, M. (Mangestuti), Joeliantina, A. (Anita), Kusnanto, K. (Kusnanto), Qomaruddin, M. B. (M), Soedirham, O. (Oedojo)   +4 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

ABSTRACTS OF RADIOLOGIC LITERATURE [PDF]

, 1975
Mingming Ma, P Begijery, Iehadi, Lander
openalex   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Quality Evaluation Models or Frameworks for Open Source Software: A Systematic Literature Review (Matching articles with categories)

, 2021
Nebi Yılmaz, Ayça Tarhan
openalex   +1 more source

Organizational Effectiveness Literature Review [PDF]

, 2000
Provides an overview and analysis of recent literature related to organizational effectiveness and management in nonprofit organizations.
Julia Davis
core  

GDNF‐RET signaling drives pulmonary neuroendocrine cell hyperplasia and allergic airway inflammation

FEBS Letters, EarlyView.
A neuroimmune interaction centered on the PNEC‐ILC2 axis in an asthma model. PNEC‐derived CGRP activates nearby ILC2s, which then release cytokines, including IL‐5 and IL‐13. These cytokines promote eosinophil and macrophage infiltration. Subsequently, GDNF produced by these cells induces PNEC hyperplasia via the GDNF receptors, RET and GFRα1 ...
Tasuku Kawano, Erina Ike, Suguru Okada, Tomoko Takahashi   +3 more
wiley   +1 more source

Bibliometric analysis of COVID-19 literature (Preprint)

, 2020
Md. Sayeed Al-Zaman
openalex   +1 more source