Results 41 to 50 of about 5,176,497 (219)

Cup‐Like Nuclei Is a Hallmark of DUX4/ERG Acute Lymphoblastic Leukemia and Reveals Cytoplasmic Mitochondria Accumulation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille   +9 more
wiley   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger   +7 more
wiley   +1 more source

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian   +13 more
wiley   +1 more source

The Iranian Other in the Novel El Maestro by Saad Al-Qorash based on Bakhtin’s Theory of the Self and the Other [PDF]

open access: yesمطالعات بین‌رشته‌ای ادبیات، هنر و علوم انسانی
The attitude towards "the other" forms the foundation of cross- cultural communication on diverse issues. The Iranian other becomes one of those "others" in the novel El Maestro, a dialogue-oriented novel in which different cultures come into contact ...
Entha Firouzi   +3 more
doaj   +1 more source

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan   +1 more
wiley   +1 more source

Thoughts on the Literature Review and GT

open access: yesGrounded Theory Review: An International Journal, 2006
Thinking about epistemic questions always reminds me of Socrates’ cave allegory. In Plato’s most famous book,The Republic, Socrates talks to a young follower named Glaucon.
Thoughts on the Literature Review and GT
doaj  

Cognitive, discursive mechanisms of digital democracy in Indonesia: from sentiment to ideology

open access: yesFrontiers in Political Science
IntroductionDigital democracy in Indonesia increasingly unfolds through government-citizen interactions on social media platforms, yet the cognitive-discursive mechanisms underlying citizens’ responses to ministerial communication remain underexplored ...
Jatmika Nurhadi   +5 more
doaj   +1 more source

The Impact of Gamified Formative Assessment on Writing Complexity, Accuracy, and Fluency: A Macro-Level Investigation in the Iranian EFL Context [PDF]

open access: yesApplied Research on English Language
Coalescing digital technologies into education has foregrounded gamified formative assessment (GFA) as a promising modality for advancing second language acquisition (SLA).
Kimia Majidi   +3 more
doaj   +1 more source

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi   +10 more
wiley   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar   +7 more
wiley   +1 more source

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