Results 91 to 100 of about 492,443 (309)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

The Author’s Modality and Sctratificational Structure of a Literary Text in Modern English [PDF]

open access: yes
Any literary text irrespective of its genre or trend represents a unique and aesthetic image of the world, created by the author according to his communicative intention and his subjective modality.
Nino Kirvalidze
core   +1 more source

Relasi Antarteks Dalam Pengkajian Sastra [PDF]

open access: yes, 2012
Inter-textual Relation in Literary Studies. Inter-texts relation exista in literary works; one work shadows the other. In studying such texts we often immediately link them with the concept of intertextuality that belongs to post-structuralism.
Sumiyadi, S. (Sumiyadi)
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Theory of Prosaics in Literature and History: Leo Tolstoy and Lion Feuchtwanger [PDF]

open access: yes, 1994
In this paper, I intend to explore the theory of prosaics, which offers a quite different approach to life and historical events in particular. This theory was introduced;by the American scholar Gary Saul Morson.
Ushatova \u2794, Angelica
core   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Litere Research Group – Literature, Literary Theory and Religion

open access: yes, 2021
O presente artigo tem o propósito de apresentar o grupo de pesquisa “Litere – Literatura, Teoria literária e Religião”, em seus diversos aspectos. Para isso, inicialmente, nos concentraremos na descrição de seu vínculo institucional e, consequentemente, de sua relação com as Ciências da Religião no Brasil; também faremos uma breve exposição de sua ...
Cappelli, Marcio, Souza, Vitor Chaves de
openaire   +1 more source

Political Aesthetics and Theory of Literature: an Open Dialogue [PDF]

open access: yes
la teoría de la literatura se encuentra hoy ante el reto de definir un nuevo espacio para el estudio de la literatura en toda su plurivocidad. Por este motivo, se propone defender la apertura de la teoría de la literatura a las propuestas realizadas ...
González Blanco, Azucena
core   +2 more sources

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

Una aproximación pragmática al estudio del texto literario: propuesta de análisis de "Betrayal" desde las teorías de la cortesía y de la relevancia [PDF]

open access: yes, 2000
The aim of this paper is to show, as many authors have done before, that literary discourse is not a special kind of language, but is instead a special use of language.
Fernández Monterde, Cristina
core  

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