Results 101 to 110 of about 492,443 (309)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

La teoría literaria latinoamericana [PDF]

open access: yes, 2014
1 archivo PDF (21 páginas). tyvlxliiiEn este trabajo busco responder a la pregunta de si existe o no una teoría literaria latinoamericana. Para ello reviso primero el concepto de teoría a fin de determinar de qué modo puede aplicarse a la literatura ...
Martínez Ramírez, Fernando
core  

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

21st-Century Theories of Literature: A Critical Reflection on an Interdisciplinary Event

open access: yesExchanges, 2014
The authors reflect upon the successes and difficulties of developing and running 21st-Century Theories of Literature: Essence, Fiction, and Value, an interdisciplinary conference held at the University of Warwick on 27-29 March 2014.
Philip Gaydon, Andrea Selleri
doaj  

Book Reviews [PDF]

open access: yes, 2012
The High Medieval Dream Vision: Poetry, Philosophy, and Literary Form (Kathryn L. Lynch) (Reviewed by James F. G. Weldon, Wilfrid Laurier University)The Death of Literature (Alvin Kernan) (Reviewed by Peter Erickson, Clark Art Institute)Alternate Worlds:
Editors, Criticism
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

TEORI SASTRA MARXIS DAN APLIKASINYA PADA PENELITIAN KARYA SASTRA ARAB MODERN

open access: yesBahasa dan Seni: Jurnal Bahasa, Sastra, Seni, dan Pengajarannya, 2012
Many works of the modern Arabic literary contain the class struggle themes, especially the struggle of the oppressed versus the oppressors. Indeed, the theme of class struggle in the works of Arabic literary is moral and social mirror of Arab society ...
Fadlil Munawwar Manshur
doaj  

Internal Chronotopic Genre Structures : The Nineteenth-Century Historical Novel in the Context of the Belgian Literary Polysystem [PDF]

open access: yes, 2010
One of the most fundamental problems of systemic approaches to literature is the question of how systemic principles might be translated into a manageable methodological framework.
Bemong, Nele
core  

Accelerated Progression of Gait Impairment in Parkinson's Disease and REM Sleep Without Atonia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with Parkinson's disease (PD) and rapid eye movement (REM) sleep without atonia (RSWA) often have more severe gait disturbances compared to PD without RSWA. The association between the presence and expression of RSWA and the rate of progression of gait impairment in PD is unknown.
Sommer L. Amundsen‐Huffmaster   +11 more
wiley   +1 more source

The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen   +5 more
wiley   +1 more source

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