Results 41 to 50 of about 8,713 (263)
This article discusses the implementation of the reader-response theory and approach in the context of a literature course (English Literature 1) taught to students enrolled at the Department of English Language and Literature, who are preparing to be ...
Spirovska Elena
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How Literature Works: Poetry and the Phenomenology of Reader Response
Reader response literary theory dominates the study of literature in the K -12 school curriculum. Because this theory reflects the student - centered, constructivist orientation currently driving curriculum development, reader response literary theory is
Patrick G. Howard
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This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Book review of Florent Coste, L’ordinaire de la littérature. Que peut (encore) la théorie littéraire ? Paris: La Fabrique, 2024. While analyzing the reasons for the decline of literary theory, the author explains the absolute necessity of literary ...
Jan Baetens
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Distant reading in literary studies: a methodology in quest of theory
Since Franco Moretti coined the successful term distant reading, quantitative/computational text analysis methods have gained wide circulation in literary studies.
Fabio Ciotti
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MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
National Code in the Literature of Kazakhstan and Central Asia
The aim of this study is to explore how the “national code,” encompassing cultural values, historical memory, and identity, is represented in Kazakh and Central Asian literature through the lenses of classical narratology and distant reading.
Alibek Baibolov +5 more
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Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Brief introduction to seven digital archives: Rossetti Archive, Dickinson Electronic Archives, The William Blake Archive, Radical Scatters, Arquivo Pessoa, Espólio Fernando Pessoa and Samuel Beckett Digital Manuscript Project.
Manuel Portela, Matheus de Brito
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