Results 101 to 110 of about 4,919,016 (310)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Agglomeration economies and the location of new information and communication technology (ICT) firms in the Netherlands [PDF]
In 2000, the world wide, rapid employment growth in the ICT-sector came to an end. Knowledge-intensive ICT-firms and -sectors in the Netherlands confirmed to this negative development trend as well. The life-cycle of the ICT-sector appears to reach a new
Atzema, Oedzge, van Oort, Frank
core
Dynamic literature mapping : typography in screen-based media [PDF]
, 2003 This paper chronicles the development of a visual map representing a literature search on key theorists and thinkers in two principal topics: Typography and New Media.
Yee, Joyce
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Knowledge Sharing Barriers of Acquisitioned Growth: A Case Study from a Software Company
International Journal of Engineering Business Management, 2013 Acquisition as a growth strategy is often burdened by subsequent unsatisfactory performance. The literature suggests that a potential cause is mismanagement of knowledge.
Marianne Kukko
doaj +1 more source
The Empirical Instituions-Growth Literature: Is Something Amiss at the Top? [PDF]
The initial publication of the Fraser Institute’s Economic Freedom of the World index prompted an explosion of empirical research on the institutions-growth relationship.
John W. Dawson
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Success Factors of Growth-Stage Digital Health Companies: Systematic Literature Review
Journal of Medical Internet ResearchBackgroundOver the past decade, digital health technologies (DHTs) have grown rapidly, driven by innovations such as electronic health records and accelerated by the COVID-19 pandemic. Increased funding and regulatory support have
Estelle Pfitzer +4 more
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Vintage capital growth theory: Three breakthroughs [PDF]
Vintage capital growth models have been at the heart of growth theory in the 60s. This research line collapsed in the late 60s with the so-called embodiment controversy and the technical sophisitication of the vintage models.
David de la Croix +2 more
core