Results 61 to 70 of about 1,420,869 (261)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Systematic review of business support practice: Establishing design features

Small Business International Review
This paper addresses the research gap associated with the core components of effective SME business support and its governance. Adopting a systematic literature review protocol, this study analyses the academic literature published between 2004 and 2025,
Ollie Jones, Matt Sutherland, Stephen Page   +2 more
doaj   +1 more source

Systematic Review of Business Incubators’ Role in Promoting Growth and Sustainability of Women Entrepreneurs [PDF]

International Journal of Management, Accounting and Economics
This systematic review investigated how business incubators contribute to the growth, performance, and sustainability of women entrepreneurs. A thorough search of studies published between 2000 and 2025 in Google Scholar and Scopus identified 27 studies ...
Joseph Magali, Anneth Rwekaza
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Precocious puberty and preserved growth after craniopharyngioma treatment: case report and literature review

Pediatric Endocrinology, Diabetes and Metabolism
Central precocious puberty (CPP), resulting from premature activation of the hypothalamic-pituitary-gonadal axis, is usually idiopathic but may arise from central nervous system tumors or head radiotherapy.
Martyna Soloch, Katarzyna Robakowska, Natalia Popłonyk, Monika Hylinska, Katarzyna Janeczek, Kamil Dyrka, Katarzyna Jończyk-Potoczna, Katarzyna Derwich, Marek Niedziela, Monika Obara-Moszyńska   +9 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Literature growth and the retrieval system in scholarly communication

Ciência da Informação, 1974
Uma série de mode los indica que o crescimento da literatura é um dos objetivos primordiais dos sistemas de comunicação da literatura. Estes são claramente bem sucedidos nas ciências; o material não relevante e a redundância são componentes úteis de suas
Bert Boyce
doaj  

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source