Results 251 to 260 of about 4,082,281 (336)

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

open access: yesAdvanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers   +10 more
wiley   +1 more source

Engineering the Link: From Genome Interaction Maps to Functional Insight

open access: yesAdvanced Biology, EarlyView.
Advances in chromosome conformation capture have revealed the genome's 3D organization, yet its causal impact on gene regulation remains elusive. This review highlights emerging genome‐engineering tools ‐ zinc fingers, TALEs, and CRISPR‐Cas9 ‐ that enable targeted manipulation of chromatin loops to dissect structure–function relationships. It discusses
Frido Petersen   +5 more
wiley   +1 more source

Quality indicators for ambulatory colectomy: literature search and expert consensus. [PDF]

open access: yesSurg Endosc
Coeckelberghs E   +7 more
europepmc   +1 more source

CALPHAD‐Guided Prediction and Interpretation of Phase Formation in Ta–Mo–Cr–Ti–Al Refractory High‐Entropy Alloys

open access: yesAdvanced Engineering Materials, EarlyView.
This study designs Ta–Mo–Cr–Ti–Al refractory high‐entropy alloys with a disordered body‐centered‐cubic A2 crystal structure aiming for improved ductility, lower density, and oxidation resistance. Four alloy compositions are identified by thermodynamic calculations.
Kateryna Khanchych   +7 more
wiley   +1 more source

Methodological challenges using routine clinical care data for real-world evidence: a rapid review utilizing a systematic literature search and focus group discussion. [PDF]

open access: yesBMC Med Res Methodol
Pfaffenlehner M   +13 more
europepmc   +1 more source

New Developments in the Field of Production and Application of Multi‐Material Wire Arc Additive Manufacturing Components: A Review

open access: yesAdvanced Engineering Materials, EarlyView.
The utilization of direct energy deposition (DED)‐arc additive manufacturing processes in industrial applications is increasing, and these processes have the potential for multi‐material applications. This work provides a overview of the state of research in DED‐arc made functional graded structures, to establish a link to potential industrial ...
Kai Treutler, Volker Wesling
wiley   +1 more source

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