Results 41 to 50 of about 15,444 (147)
Women in space: A review of known physiological adaptations and health perspectives
Experimental Physiology, EarlyView.Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford +4 more
wiley +1 more source
Pharmacological ResearchImmune checkpoint inhibitors (ICIs) are essential for urothelial carcinoma (UC) treatment. Fibroblast growth factor receptor (FGFR) alterations, as common oncogenic drivers in UC, have been reported to drive T cell depletion of UC immune microenvironment
Yuxuan Song +5 more
doaj +1 more source
Ожирение и метаболизм, 2016 Objectives: To study the lipid metabolism and secretion of GLP-1 and GIP in obese patients with type 2 diabetes before and 3 months after biliopancreatic diversion (BPD) in Hess-Marceau modification.Materials and methods: 22 patients (44 [38.0; 55.0 ...
Ekaterina Ershova +2 more
doaj +1 more source
DEN Open, Volume 6, Issue 1, April 2026.Abstract Objectives Esophagogastroduodenoscopy (EGD) is vital for diagnosing and treating upper gastrointestinal symptoms, but patient discomfort and anxiety can affect procedural outcomes. This study aimed to compare the effectiveness of topical analgesics with and without Entonox during EGD in terms of procedural success, patient tolerance, and ...
Papiroon Noitasaeng +3 more
wiley +1 more source
DEN Open, Volume 6, Issue 1, April 2026.ABSTRACT Objectives To evaluate the clinical outcomes of peroral cholangiopancreatoscopy (POCPS) using the 9‐Fr eyeMAX for the diagnosis of pancreatobiliary diseases. Methods This retrospective study enrolled 43 patients who underwent POCPS using the 9‐Fr eyeMAX for diagnostic procedures at two tertiary referral centers between May 2023 and November ...
Haruo Miwa +17 more
wiley +1 more source
Frontiers in ImmunologyImmune checkpoint inhibitors (ICIs) have revolutionized the treatment of systemic cancer therapy. During disinhibiting the antitumor responses of immune system, ICIs may also cause unique immune-related adverse events (irAEs) which could affect any organ.
Jiaxiang Ji +7 more
doaj +1 more source
DEN Open, Volume 6, Issue 1, April 2026.ABSTRACT Objective To evaluate the effectiveness of spontaneously dislodging biliary stent (SDBS) placement in preventing acute cholangitis after endoscopic retrograde cholangiopancreatography (ERCP) in patients with asymptomatic bile duct stones. Methods This retrospective, single‐center study included 63 patients (mean age, 73 ± 11 years; 43 men) who
Shinichi Nihei +9 more
wiley +1 more source
Ожирение и метаболизм, 2015 Introduction: a significant improvement was shown in metabolic control at the early stages after BPD, which was associated with GLP-1 and was regardless of weight loss.Aim: to study the secretion of GLP-1, GIP, insulin and glucagon and their relationship
Ivan Ivanovich Dedov +3 more
doaj +1 more source
DEN Open, Volume 6, Issue 1, April 2026.Endoscopic ultrasound‐guided gallbladder drainage using a double‐pigtail plastic stent (DPPS) harbors the risk of bile leakage and pneumoperitoneum through the anastomosis site. When the inner sheath of the DPPS system is retracted halfway back into the stent, multiple side holes emerge on the stent end, which accelerates the active gallbladder lavage.
Tesshin Ban +7 more
wiley +1 more source
DEN Open, Volume 6, Issue 1, April 2026.ABSTRACT Objectives Post‐endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) is an adverse event of ERCP‐related procedures. The present study aimed to evaluate the incidence of PEP in patients with an intact papilla who underwent ERCP for common bile duct stones and identify risk factors and preventive measures for PEP.
Toru Maruo +8 more
wiley +1 more source