Results 41 to 50 of about 50,749 (218)

Do drugs approved via expedited approval pathways have therapeutic advantages? A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer, Eliza J. McEwin, Zhicheng Wang, Joel Lexchin, Barbara Mintzes   +4 more
wiley   +1 more source

Defining a comprehensive set of value assessment criteria for funders of drug repurposing initiatives

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aims to develop a structured list of value assessment criteria for drug repurposing (DR) projects designed to support consistent, evidence‐informed decision‐making by funders. The assessment criteria were developed within the REMEDi4ALL project, a multi‐stakeholder Horizon Europe funded initiative to advance DR and were validated ...
Dalma Hosszú, Kristóf Gyöngyösi, András Perényi, Helene G. van der Meer, Dunja Huijbers, Pan Pantziarka, András Inotai, Donald C. Lo, Rick Thompson, Zoltán Kaló, Marcell Csanádi   +10 more
wiley   +1 more source

Brief rewarming blunts hypothermia-induced alterations in sensation, motor drive and cognition

Frontiers in Physiology, 2016
Background: It is well known that cold exposure experienced during occupational or recreational activities may adversely affect motor, cognitive performance and health. Most research has used prolonged passive external rewarming modalities and focused on
Marius Brazaitis, Henrikas Paulauskas, Albertas Skurvydas, Henning Budde, Henning Budde, Laura Daniuseviciute, Nerijus Eimantas   +6 more
doaj   +1 more source

Migrant success in UK Education: Are there lessons for government social mobility policy?

British Educational Research Journal, EarlyView.
Abstract The school achievement and career aspirations of 23 sixth form students at a multi‐cultural urban academy in the UK are explored through interviews. The sample includes 16 s‐generation migrants, 6 UK‐born students with migrant parents and 1 UK‐born student, selected to represent a cohort of over 300 post‐16 learners.
Bernard Barker, Kate Hoskins
wiley   +1 more source

The Effect of Strength Training on the Quality of Life and Cognitive Functions of Elderly People

Baltic Journal of Sport and Health Sciences
Background: The evidence from research shows positive effects of physical exercise, both aerobic and resistance training, and their combination, on cognitive performance.
Ernesta Klimavičiūtė, Sandra Naujalė , Lina Mickevičienė , Erika Krasinskė, Margarita Drozdova – Statkevičienė , Vida Janina Česnaitienė   +5 more
doaj   +1 more source

Stress-induced Hydride Reorientation and Cracking in Fuel Cladding Tube

Medžiagotyra, 2014
Goal of this research was to find out if reorientation can influence cladding failure and determine conditions and possible mechanism of failure.  Reorientation tests were done on zircaloy nuclear fuel cladding specimens.
Albertas GRYBĖNAS, Vidas MAKAREVIČIUS, Tadas KALIATKA, Gintautas DUNDULIS, Rita KRIŪKIENĖ   +4 more
doaj   +1 more source

University strategy in transnational higher education: The strategic approaches of newly established and ‘small’ international branch campuses

British Educational Research Journal, EarlyView.
Abstract Newly established international branch campuses (IBCs) commence operations without a student body, and even after several years, many institutions fail to grow beyond 500 students. Despite having unique strategic needs, small IBCs are largely overlooked in the higher education literature.
Stephen Wilkins, Joe Hazzam
wiley   +1 more source

Real-World Longitudinal Sleep Changes Associated With a Wearable Transcutaneous Vagus Nerve Stimulation Device: Analysis of Consumer Data From the United States

Reabilitacijos Mokslai: Slauga, Kineziterapija, Ergoterapija
Background and Aim. Non-invasive transcutaneous vagus nerve stimulation (tVNS) is increasingly investigated as a neuromodulation approach for improving sleep and autonomic regulation.
Domas Pauliukevičius, Viktorija Juodeikytė, Viktorija Juodeikytė, Mantas Mickevičius, Dalia Mickevičienė , Inga Lukonaitienė   +5 more
doaj   +1 more source

Detection and analysis of triterpenic compounds in apple extracts

International Journal of Food Properties, 2018
A new technique for the rapid detection and analysis of triterpenic compounds in apple extracts using HPLC was developed and validated. The main advantage of this technique is the short duration of the analysis – this makes this technique superior to ...
Aurita Butkevičiūtė, Mindaugas Liaudanskas, Darius Kviklys, Kristina Zymonė, Raimondas Raudonis, Jonas Viškelis, Norbertas Uselis, Valdimaras Janulis   +7 more
doaj   +1 more source

Past and Future of Sustainability Indicator Research in Agribusiness: A Bibliometric and Forecasting Analysis

Business Strategy and the Environment, EarlyView.
ABSTRACT This study offers a forward‐looking assessment of sustainability indicator research in agribusiness by integrating bibliometric mapping with ARIMA‐based forecasting. Analysing 403 Scopus‐indexed articles, bibliographic‐coupling analysis identifies three contemporary thematic domains: Techno‐Managerial Sustainability, Systemic and ...
Marcelo Kratz Mendes, Olga Cam, Aurora Carneiro Zen, Roger de Bem Jaeger, Daniela Callegaro‐de‐Menezes, Juliana Matos de Meira   +5 more
wiley   +1 more source