Results 181 to 190 of about 112,365 (262)

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

open access: yesPediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu   +4 more
wiley   +1 more source

Proteomic Profiling of Primary Hippocampal Neurons Reveals Noncanonical GFAP Expression and Metabolic Adaptations in Glia‐Free Culture

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Despite their widespread use as a research model, a comprehensive, quantitative proteomic profile of the cultured hippocampal neurons has remained unexplored. Here, we provide the first global proteomic characterization of primary murine hippocampal neurons cultured for 14 days under near‐physiological glucose conditions (2.5 mM).
Dominika Drulis‐Fajdasz   +6 more
wiley   +1 more source

The Age and Origin of Block Deposits in the Victorian Alps, Australia

open access: yesPermafrost and Periglacial Processes, EarlyView.
ABSTRACT Large periglacial block deposits are found in the mountains of southeastern Australia. Despite their widespread distribution, their mode of formation and age are poorly understood. These landforms hold considerable potential to shed light on the nature of cooling during glacial periods. In this paper we present a new study of block deposits in
Timothy T. Barrows   +4 more
wiley   +1 more source

Simulating Arctic Greening: Microbial Responses in Thawing Yedoma Permafrost

open access: yesPermafrost and Periglacial Processes, EarlyView.
ABSTRACT Arctic permafrost soils and sediments store vast amounts of organic carbon. With global warming intensifying, these soils are increasingly exposed to microbial decomposition. Further, Arctic warming and longer growing seasons drive regional greening, potentially accelerating the degradation of the previously frozen organic matter through ...
André Faust   +3 more
wiley   +1 more source

Range‐wide sampling reveals cryptic lineages but largely conserved mycorrhizal associations in the Japanese fairy lantern Thismia kobensis

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
The jewel‐like flowers of Thismia are as rare as they are beautiful, often recorded from only a single site per species. Access to 15 populations of T. kobensis has enabled an uncommon, range‐wide assessment of morphology, genetics, and fungal partners. Our analyses showed that T.
Kenji Suetsugu   +4 more
wiley   +1 more source

Enhancing Detection of Feline Chronic Kidney Disease Through Smart Litter Box Monitoring. [PDF]

open access: yesAnimals (Basel)
Langenfeld-McCoy N   +8 more
europepmc   +1 more source

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