Results 41 to 50 of about 142,609 (269)

SIRT5–RAC2 Axis Drives Monocyte‐to‐Macrophage Differentiation to Promote Inflammatory Injury in Premature Ovarian Insufficiency

Advanced Science, EarlyView.
SIRT5 desuccinylates and stabilizes RAC2, activating CSF1R‐dependent signaling to drive monocyte differentiation into M0 macrophages and their polarization toward pro‐inflammatory M1 phenotypes in CTX‐induced premature ovarian insufficiency. Inhibiting the SIRT5‐RAC2 axis attenuates inflammation, reduces granulosa cell apoptosis, and preserves ...
Wenjing TanTai, Yaqi Li, Shengnan Liu, Minjuan Wu, Zhixiao Liu, Junfeng Jiang, Jingjing Chen, Xiaoding Xu, Li Li, Chaoqun Li, Fang Zhao, Ye Liu, Haitao Ni, Tengfei Zhang, Mingjuan Xu, Chaofeng Han   +15 more
wiley   +1 more source

Salinity Mediates Tamarix chinensis Litter Decomposition to Enhance Soil Enzyme Activity in Coastal Saline–Alkali Soils

Plants
The aim of this study was to explore the decomposition characteristics of Tamarix chinensis litter and its soil-improving capacity under different salinities.
Yue Lu, Lingtai Kong, Shihui Li, Pan Lun, Fanglei Gao, Qiqi Cao, Jiangbao Xia   +6 more
doaj   +1 more source

Produção de serapilheira em uma floresta de Araucaria angustifolia (Bertol.) Kuntze no município de Pinhal Grande-RS Litterfall in an Araucaria angustifolia (Bertol.) Kuntze forest in Pinhal Grande, RS

Revista Árvore, 2004
O objetivo do trabalho foi avaliar a deposição anual de serapilheira, bem como a devolução de macronutrientes (N, P, K, Ca e Mg) em um povoamento de Araucaria angustifolia com 17 anos de idade, em Pinhal Grande-RS.
Mauro Valdir Schumacher, Eleandro José Brun, Jonas Inoé Hernandes, Flávia Gizele König   +3 more
doaj   +1 more source

miR‐135a‐5p Is a Promising Target to Prevent the Glomerulosclerosis Associated with Podocyte Developmental Toxicity in Offspring Induced by Prenatal Dexamethasone Exposure

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao, Haiyun Chen, Yanan Zhu, Zhiping Xia, Hangyuan He, Yutang Liu, Tianshu Yang, Hui Wang, Ying Ao   +8 more
wiley   +1 more source

Effects of mixed plantation of Pinus massoniana and Castanopsis hystrix at different stand ages on litter and soil carbon storage

Guangxi Zhiwu
Litter is an important part of forest productivity, and its productivity and stoichiometric ratio(high N and low C:N, C:P and N:P, which facilitate litter decomposition)are vital in regulating soil carbon dynamics through decomposition rate modulation ...
LUO Xinyu, HE Peng, LIU Runhong, SONG Huiqing, QIN Huizhen, CEN Qilan, SHEN Weijun*
doaj   +1 more source

Spatial Transcriptomics of TMJ Reveals a Remodeling Fibroblast‐Immune Microenvironment Driving Arthritis Pain

Advanced Science, EarlyView.
Spatial transcriptomics reveals a remodeled fibroblast‐immune microenvironment in the temporomandibular joint (TMJ) during arthritis. By combining seqFISH with genetic mouse models, this study uncovers TMJ spatial cell atalas, macrophage‐fibroblast crosstalk, and cytokine signaling pathways driving TMJ inflammation and pain.
Ziying Lin, Supawadee Jariyasakulroj, Yang Shu, Jingyi Chen, Qing Chang, Pao‐Fen Ko, Yuyueyang Qiu, Feixiang Chen, David Ahn, Zhen Zhao, Jian‐Fu Chen   +10 more
wiley   +1 more source

Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis

Hepatology, EarlyView., 2022
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr, Benedikt Kaufmann, Maria Eugenia Inzaugarat, Theresa Maria Holtmann, Lukas Geisler, Jana Hundertmark, Marlene Sophia Kohlhepp, Laela M. Boosheri, Daisy R. Chilin‐Fuentes, Amanda Birmingham, Kathleen M. Fisch, Joel D. Schilling, Sven H. Loosen, Christian Trautwein, Christoph Roderburg, Münevver Demir, Frank Tacke, Hal M. Hoffman, Ariel E. Feldstein, Alexander Wree   +19 more
wiley   +1 more source

Níveis de treonina digestível em dietas para fêmeas suínas de alto potencial genético em lactação sob condições de alta temperatura ambiente Digestible threonine levels of high-producing lactating sows maintained under high temperature environment conditions

Revista Brasileira de Zootecnia, 2007
Foram utilizadas 52 fêmeas suínas em lactação distribuídas em delineamento experimental de blocos ao acaso, composto de quatro níveis de treonina digestível (0,64; 0,67; 0,70 e 0,73%) na dieta e 13 repetições, em que cada unidade experimental foi ...
Charles Kiefer, Aloízio Soares Ferreira, Rita Flávia Miranda de Oliveira, Juarez Lopes Donzele, Alfredo Sampaio Carrijo, Francisco Carlos de Oliveira Silva   +5 more
doaj   +1 more source

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

Advanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling, Aïda Yakhlef Sanchez, Nicolas Thelen, Müge Senarisoy, Maria Hogg, Steven Condamine, Andrea Lelli, Emilia Wysocka, Pranav Patni, Sandrine Vitry, Kerem Yasin Yildizhan, Sébastien Le Gal, Sylvie Nouaille, Michael R. Bowl, Marc Thiry, Didier Dulon, Sedigheh Delmaghani, Aziz El‐Amraoui   +17 more
wiley   +1 more source

Níveis de lisina em rações para fêmeas suínas em lactação Lysine levels in diets for lactating sows

Revista Brasileira de Zootecnia, 2006
Foram utilizadas 65 porcas (Large White x Landrace) com 217,36 ± 21,35 kg para avaliação de diferentes níveis de lisina total (0,950; 1,025; 1,100; 1,175 e 1,250%) na ração para a fase de 21 dias de lactação.
Christiane Garcia Vilela Nunes, Rita Flavia Miranda de Oliveira, Juarez Lopes Donzele, Will Pereira de Oliveira, Bruno Alexander Nunes Silva, Marvio Lobão Teixeira de Abreu   +5 more
doaj   +1 more source