Results 41 to 50 of about 612,365 (355)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Making the most of life: environmental choice during rearing enhances the ability of laying hens to take opportunities

open access: yesFrontiers in Veterinary Science
IntroductionThe potential of aviary housing for improving laying hen (Gallus gallus domesticus) welfare will be constrained if rearing conditions limit the hens’ behavioral ability to take opportunities. Incorporating theories on developmental plasticity
Lena Skånberg   +6 more
doaj   +1 more source

Leaftronics: Bio‐Fractal Scaffolds From Leaf Venation for Low‐Waste Electronics

open access: yesAdvanced Materials, EarlyView.
“Leaftronics” transforms naturally evolved leaf venation into quasi‐fractal scaffolds for sustainable electronics. Polymer‐infiltrated leaf skeletons can be used to fabricate ultra‐smooth, reflow‐ and thin‐film‐compatible decomposable substrates, while making the same lignocellulose networks conducting results in flexible transparent electrodes.
Rakesh Rajendran Nair   +3 more
wiley   +1 more source

First Assessment of Micro-Litter Ingested by Dolphins, Sea Turtles and Monk Seals Found Stranded along the Coasts of Samos Island, Greece

open access: yesAnimals, 2022
This study is the first to assess the occurrence of micro-litter ingested by marine megafauna in the north-eastern Aegean Sea. A total of 25 specimens from four species of marine mammals, including dolphins and monk seals, and two species of sea turtles,
Guido Pietroluongo   +4 more
doaj   +1 more source

Are low-producing plants sequestering carbon at a geater rate than high-producing plants? : a test within the genus Chionochloa : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Ecology at Massey University, Palmerston North, New Zealand [PDF]

open access: yes, 2016
Plant life and primary production play an important role in the global carbon (C) cycle through the fixing of atmospheric C into the terrestrial biosphere. However, the sequestration of C into the soil not only depends on the rate of plant productivity,
Dickson, Matthew Phillip Sijbe
core  

The Uppsala APP Mutation Promotes Wild‐Type Amyloid‐β Aggregation and Deposition In Vivo

open access: yesAdvanced Science, EarlyView.
We investigated in vivo cross‐seeding of amyloid‐β (Aβ) isoforms in transgenic mice co‐expressing wild‐typeAβ and the Uppsala‐mutant Aβ variant (AβUpp), lacking six central residues. Weleveraged MALDI‐MS imaging and hyperspectral microscopy to follow spatio‐temporalAβ deposition.
Junyue Ge   +14 more
wiley   +1 more source

High litter moisture content suppresses litter ammonia volatilization

open access: yesPoultry Science, 2011
With global food demand expected to increase by 100% in the next 50 yr, urgency to combine comprehensive strategies for sustainable, efficacious, and environmentally sensible agronomic practices has never been greater. One effort for US meat bird management is to reduce NH(3) volatilization from litter to create a better growing environment for the ...
D M, Miles, D E, Rowe, T C, Cathcart
openaire   +2 more sources

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

open access: yesAdvanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou   +22 more
wiley   +1 more source

Influence of lambing type on body weight changes and productive efficiency of Blackbelly × Pelibuey multiparous ewes in lactation. Technical note

open access: yesRevista Científica
During lactation, ewes have a high demand for nutrients, which is frequently not met by voluntary intake in grazing, a situation that causes a reduction in body weight.
Benigno Morales–Carrillo   +3 more
doaj   +1 more source

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan   +17 more
wiley   +1 more source

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