Results 81 to 90 of about 36,642 (249)

Maternal‐Fetal Administration of Risdiplam Partially Rescues the SMNΔ7 Mouse Model of Spinal Muscular Atrophy

open access: yesAnnals of Neurology, EarlyView.
Objective Spinal muscular atrophy (SMA) is caused by deletions or mutations in the survival motor neuron 1 (SMN1) gene and subsequent reduction in the expression of survival motor neuron (SMN) protein. The disease is characterized by degeneration of α motor neurons and subsequent muscle atrophy.
Emma R. Sutton   +4 more
wiley   +1 more source

Evolutionary, Functional and Mechanistic Characterisation of Microbial Terpene Synthase‐Like Genes From Springtails

open access: yesAngewandte Chemie International Edition, EarlyView.
A genome analysis revealed the presence of many bacterial‐type terpene synthases in springtails. Four enzymes from Sinella curviseta were functionally characterised, resulting in the isolation of several compounds including sinellene ether, the first diterpene ether identified from a terpene synthase that represents a novel skeleton.
Min Wang   +5 more
wiley   +1 more source

Role of soft tissue and bone interactions in the developmental integration and modularity of the skull in neural crest‐specific gap junction alpha‐1 knockout mice

open access: yesThe Anatomical Record, EarlyView.
Abstract The vertebrate skull is composed of bones derived from neural crest cells and mesoderm. The evolutionary capacity of the skull has been linked, in part, to the emergence of neural crest cells; however, this increased capacity for evolutionary change requires that variation within neural crest‐ and mesoderm‐derived bones remains partly ...
Alyssa C. Moore   +5 more
wiley   +1 more source

A multi-year tracking of floating marine litter from satellite images in the Pearl River Estuary

open access: yesCambridge Prisms: Plastics
Marine litter, predominantly plastic, is a global environmental threat, which management is hindered by the absence of large-scale monitoring tools. This study extends a framework to detect Floating Marine Macro-Litter (FMML) in the complex waters of the
Fengyuan Liang   +3 more
doaj   +1 more source

SOX6 is expressed in various cell lineages in the developing mouse heart and contributes to proper valvuloseptal development

open access: yesThe Anatomical Record, EarlyView.
Abstract Cells derived from the endocardium, epicardium, cardiac neural crest, and second heart field play a critical role in the formation of the valvuloseptal structures of the heart. Previous studies have shown that the expression of the transcription factor SOX9 in these cell populations is essential in the regulation of this process.
Hannah G. Tarolli   +6 more
wiley   +1 more source

Heat Stress and Gut Microbiome Dynamics in Poultry: Interplay, Consequences, and Mitigation Strategies

open access: yesAnimal Research and One Health, EarlyView.
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke   +9 more
wiley   +1 more source

Genomic Structural Variations Provide Insights Into Litter Size and Teat Number Traits in Hu Sheep

open access: yesAnimal Research and One Health, EarlyView.
Here, we conducted whole genome sequencing on 300 Hu sheep with an average depth of 16.51X. Two candidate genes associated with litter size and teat number traits were identified, namely MAST2 and AFDN. ABSTRACT Litter size and the teat number are important economic indicators in sheep production.
Xin Xiang   +3 more
wiley   +1 more source

Comparative Assessment of Landsat‐8 and SPOT‐7 Satellite Data With Field Spectral Measurements for Estimating Plant Diversity in Sandy Grasslands

open access: yesBiological Diversity, EarlyView.
We compared Landsat‐8 OLI, SPOT, and hyperspectral data for estimating vascular plant diversity in China's Hunshandak Sandland. SPOT data showed the strongest correlation with alpha diversity, followed by hyperspectral data, with Landsat‐8 performing the weakest.
Ying Ye   +3 more
wiley   +1 more source

The evidence base for ranger patrol effectiveness in conservation and how to improve it

open access: yesBiological Reviews, EarlyView.
ABSTRACT Ranger patrols are a cornerstone of wildlife protection efforts around the world and occur across all ecological governance systems. Evidence that patrols reduce threats to wildlife and enable their recovery has not been systematically examined previously.
Trina Rytwinski   +19 more
wiley   +1 more source

Development of an electromechanical device for real-time detection of litter moisture in commercial broiler

open access: yesSmart Agricultural Technology
Broiler litter quality is a critical factor in industrial broiler production systems, as it affects the environment and animal welfare. The litter is composed of thermal insulating materials such as wood shavings, peanut shells and, rice, among others ...
Glauber da Rocha Balthazar   +3 more
doaj   +1 more source

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