Results 191 to 200 of about 294,374 (349)

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

open access: yesPediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu   +4 more
wiley   +1 more source

Proteomic Profiling of Primary Hippocampal Neurons Reveals Noncanonical GFAP Expression and Metabolic Adaptations in Glia‐Free Culture

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Despite their widespread use as a research model, a comprehensive, quantitative proteomic profile of the cultured hippocampal neurons has remained unexplored. Here, we provide the first global proteomic characterization of primary murine hippocampal neurons cultured for 14 days under near‐physiological glucose conditions (2.5 mM).
Dominika Drulis‐Fajdasz   +6 more
wiley   +1 more source

The Age and Origin of Block Deposits in the Victorian Alps, Australia

open access: yesPermafrost and Periglacial Processes, EarlyView.
ABSTRACT Large periglacial block deposits are found in the mountains of southeastern Australia. Despite their widespread distribution, their mode of formation and age are poorly understood. These landforms hold considerable potential to shed light on the nature of cooling during glacial periods. In this paper we present a new study of block deposits in
Timothy T. Barrows   +4 more
wiley   +1 more source

Whole genome sequences of 297 Duolang sheep for litter size. [PDF]

open access: yesSci Data
Fang C   +5 more
europepmc   +1 more source

Metabolomic Profiling Reveals the Difference in Reproductive Metabolism and Oxidative Stress in the Breeding Pigeon (<i>Columba Livia</i>) with Different Litter Sizes

open access: green, 2022
Suiling Zhang   +9 more
openalex   +1 more source

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