Results 121 to 130 of about 8,186,764 (283)

CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression

Advanced Science, EarlyView.
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao, Lijuan Song, Meiqian Xu, Tianhao Liang, Yixuan Chen, Gui Chen, Zaihuan Lin, Huakang Du, Guofei Feng, Zhiming Feng, Qi Zhang, Fan Pan, Saixuan Yang, Xinyin Zhang, Wenxu Peng, Tianlong Li, Zhuoshen Lin, Yabang Chen, Jiayi Liu, Baoxin Peng, Yan Liu, Xing Niu, Ting Li, Chengyu Huang, Ke Mo, Jianlei Xie, Yu Zou, Xiaowen Zhang   +27 more
wiley   +1 more source

Changes in glaciers and climate in the Karakoram since the Little Ice Age

Advances in Climate Change Research
Reconstructing the long-term context of glacier changes in the Karakoram helps to further understand the anomalous behavior of its glaciers particularly under a changing climate.
Hong-Jie Zhang, Xiang-Ke Xu, Ying-Kui Li, Liang Liu, Ya-Qing Sun, Jiu-Le Li   +5 more
doaj   +1 more source

An Anti‐Amyloidogenic Approach to Specifically Block Memory Consolidation in Mice for Therapeutic Intervention

Advanced Science, EarlyView.
Functional amyloid conversion of the translation regulator CPEB3 is essential for long‐term memory persistence. This study demonstrates that targeting this molecular switch with the anti‐amyloidogenic peptide QBP1 selectively blocks CPEB3 fibrillation without disrupting phase separation.
Paula López‐García, Kerry R. McGreevy, Maria Eugenia Vaquero, Juan M. Suarez‐Rivero, Antonio Moreno‐Rodríguez, Antonio J. Pérez‐Pulido, Daniel Ramírez de Mingo, Anna Pallé, Helena Akiko Popiel, Andrea Santi, Mario D. Cordero, José Luis Trejo, Yoshitaka Nagai, Mariano Carrión‐Vázquez   +13 more
wiley   +1 more source

Little ice age in the documentary sources

, 2016
This diploma thesis focuses on the description of the period called Little Ice Age based on documentary sources information and the early meteorological measurements. This phase lasted approximatelly from 13th century till mid 19th century.
Žáková, Nikola
core  

Supplementary_material – Supplemental material for A multi-model analysis of ‘Little Ice Age’ climate over China

, 2019
Supplemental material, Supplementary_material for A multi-model analysis of ‘Little Ice Age’ climate over China by Xuecheng Zhou, Dabang Jiang and Xianmei Lang in The ...
Dabang Jiang (6297140), Xianmei Lang (6297143), Xuecheng Zhou (6297137)   +2 more
core   +1 more source

Climate of little ice age in japan [PDF]

The climate during the period from 16th to 19th century in Japan was reconstructed by the historical weather records of the Feudal Clan Tsugaru. Fluctuations of monthly precipitation frequency, snowfall ratio and so on were examined, and deviations of ...
タガミ, ヨシオ, Maejima, Ikuo, Tagami, Yoshio, マエジマ, イクオ, 7718, 7717   +5 more
core   +1 more source

Understanding glacier dynamics since the Little Ice Age in the sub-basins of Chandrabhaga Basin, Lahaul Himalaya, India

Frontiers in Water
This study quantifies the changes in glaciers since the Little Ice Age (LIA) in the sub-basins of the Chandrabhaga River basin of Lahaul Himalaya, Himachal Pradesh, India.
Rakesh Saini, Ganga Sagar Bhagat, Ganga Sagar Bhagat, Mohd Ramiz, Sakshi Mankotia   +4 more
doaj   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Ice Age Floods Institute

, 2008
This site describes Ice Age glaciers and immense floods of glacial meltwater that swept across the Pacific Northwest (18,000-12,000 years ago and earlier), affecting the landscape from Montana to Washington and Oregon, sculpting the Columbia River Basin,

core  

Evidence for extreme export of Arctic sea ice leading the abrupt onset of the Little Ice Age. [PDF]

Sci Adv, 2020
Miles MW, Andresen CS, Dylmer CV.
europepmc   +1 more source