Results 191 to 200 of about 124,423 (252)

Shifting winter atmospheric teleconnections to the North Pacific reconcile Younger-Dryas and Holocene δ¹⁸O signals. [PDF]

Nat Commun
Anderson L, Finney BP, Baxter WB.
europepmc   +1 more source

Engineering Neuronal Network Connectivity Through Precise and Scalable Electrical Modulation

Advanced Science, EarlyView.
This study presents a scalable all‐electrical method for precise neuronal‐circuit reconfiguration based on high‐density microelectrode arrays. By employing biologically inspired plasticity rules, targeted connectivity changes were successfully induced and quantified across diverse neuronal preparations.
Sreedhar S. Kumar, Yannaël Bossard, Rachel Sava, Tobias Gänswein, Lorenca Sadiraj, Jean‐Samuel Dupré, Manuel Schröter, J. Gray Camp, Fernando Cardes, Julian Bartram, Andreas Hierlemann   +10 more
wiley   +1 more source

Historical redlining, breast cancer survival, and the mediating and modifying role of contemporary neighborhood socioeconomic conditions. [PDF]

Am J Epidemiol
Lima SM, Palermo TM, Tian L, Lee FF, Insaf TZ, Taylor HL, Meier HCS, Erwin DO, Ochs-Balcom HM.   +8 more
europepmc   +1 more source

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

Advanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang, Chenyu Deng, Zhengrong Gao, Chen Chen, Huimin Zheng, Yue Yang, Yan Wei   +6 more
wiley   +1 more source

Good vibrations: Exploring how orbital resonance shapes the Galilean moons. [PDF]

Nat Commun
Veenstra A, van Woerkom Q, Marzolini A, Fayolle S, Filice V.   +4 more
europepmc   +1 more source

Aptamer‐Directed Porous DNA Nanocomposite Hydrogel for Active Pulp Preservation: Immunomodulation, Stem Cell Recruitment and Reparative Dentinogenesis

Advanced Science, EarlyView.
This study presents an injectable DNA‐based porous hydrogel integrating catechol motifs and targeting aptamers for pulpitis management. Upon in situ crosslinking, the scaffold actively recruits endogenous dental pulp stem cells, restores redox homeostasis, and modulates immune responses.
Luhui Cai, Huan Yu, Zihan Ni, Kan Chen, I‐Chen Tsai, Zeyu Bao, Shuo Sun, Weichang Li, Yunhua Chen, Qiong Xu   +9 more
wiley   +1 more source

Millennial-to-orbital-scale subsurface ocean warming and Polynya formation off Dronning Maud Land during the last glacial. [PDF]

Nat Commun
Pinho TML, Nürnberg D, Nele Meckler A, Mollenhauer G, Müller J, Lohmann G, Lembke-Jene L, Hidayat S, Rigalleau V, Lamy F, Tiedemann R.   +10 more
europepmc   +1 more source

Pollen assemblages in <i>Tamarix</i> cone sediments and their implications for environmental change in the Southeastern Qaidam basin over the past 600 years. [PDF]

Front Plant Sci
Hou X, Zhao Y, Guo X, Song S, Feng Y, Dong Y.   +5 more
europepmc   +1 more source

Augmentative and Alternative Communication Generative Language Intervention: A Randomized Controlled Trial. [PDF]

J Speech Lang Hear Res
Binger C, Harrington N, Hahs-Vaughn DL, Kent-Walsh J.   +3 more
europepmc   +1 more source

Laboratory tests for bovine respiratory bacteria and antimicrobial resistance in commercial feedlot cattle: comparing culture, long-read metagenomics, and recombinase polymerase amplification. [PDF]

Front Microbiol
Otto SJG, McLeod L, McCarthy EL, Funk T, Lacoste SR, Chai Z, Links MG, Barlow LD, Gow SP, Ramsay D, Zaheer R, McAllister TA, Stothard P, Hill JE, Waldner CL.   +14 more
europepmc   +1 more source