Results 221 to 230 of about 8,186,764 (283)

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

Advanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian, Qianyu Wang, Wenyan Gao, Xianfeng Li, Jiawen Fan, Xiaoliang Wu, Siqi Liu, Xiangdong Ming, Danna Yeerken, Mutian Shen, Qingjie Min, Qimin Zhan, Yan Wang   +12 more
wiley   +1 more source

A comparative study on executive function of adolescent athletes in different winter sports. [PDF]

BMC Sports Sci Med Rehabil
Wang J, Wang F, Gao G, Liu C, Shi P.
europepmc   +1 more source

Niche‐Mediated Neural Priming Enables Robust and Scalable Generation of Human Choroid Plexus Organoids

Advanced Science, EarlyView.
Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen, Liangxia Jiang, Xianbin Wang, Lili Zhong, Rongcan Luo, Min Su, Liangzhao Chu, Peng Luo   +7 more
wiley   +1 more source

Projections of 21st-century sea-level fall along coastal Greenland. [PDF]

Nat Commun
Lewright L, Austermann J, Piecuch CG, Adhikari S, Davis JL, Milne GA, Paxman GJG.   +6 more
europepmc   +1 more source

D4F‐Functionalized Ceria Nanozyme‐CasRx Platform Suppresses STING and Reprograms the Renal Immune Niche in Acute Kidney Injury

Advanced Science, EarlyView.
D4F‐functionalized ceria nanozyme–CasRx nanoparticles preferentially target renal macrophages through SR‐B1‐mediated uptake in ischemia–reperfusion injury. Ceria scavenges excessive ROS, while CasRx silences STING signaling, shifting macrophages toward a less inflammatory, pro‐resolving state and increasing the proportion of regulatory T cells.
Weibo Chen, Ming Li, Xuesheng Wang, Jiajia Sun, Ziyuan Zhang, Yongfeng Gong, Benkang Shi, Nengwang Yu, Yunuo Mao, Shengtian Zhao, Xiulin Zhang, Liqiang Guo   +11 more
wiley   +1 more source

Beryllium 10 in Antarctica over the last seven millennia. [PDF]

Sci Data
Jouzel J, Cauquoin A, Bard E, Zhang L, Hou S, Wu Z, Zhou W, Lipenkov V, Petit JR, Raisbeck G, Yiou F.   +10 more
europepmc   +1 more source

Early Tracheal and Salivary miRNAs in Extremely Preterm Infants Predict Bronchopulmonary Dysplasia-Related Pulmonary Hypertension. [PDF]

Pulm Circ
Li T, Zhang S, Aluquin V, Donnelly A, Stephens H, Sharma S, Hicks SD, Liu D, Austin E, Siddaiah R.   +9 more
europepmc   +1 more source

Petermann Glacier on the brink: Progress, challenges and insights. [PDF]

Sci Adv
Fahrner D, Colgan WT, MacGregor JA, Washam P, Løkkegaard A, Khan SA.   +5 more
europepmc   +1 more source

Rock carving depth reflects carvers' geological insight. [PDF]

PLoS One
Liebl C, Peternell M, Horn C, Ling J, Moyano Di Carlo J, Green A, Potter R.   +6 more
europepmc   +1 more source

Volcanic eruptions caused weakening AMOC during the preindustrial past millennium. [PDF]

Nat Commun
Chen K, Liu Z, Ning L, Liu J, Lei L, Mann ME, Yan M, Sun W, Sun H, Hu W, Gu P, Bao Y, Qin Y, Xing F, Li L, Du J, Wen Q.   +16 more
europepmc   +1 more source