Results 191 to 200 of about 231,839 (268)

Survival Prospects of Wild Birds Depending on the Type of Injury and Other Stressors Leading to Hospitalisation: A Long-Term (1988-2020) Retrospective Study from an Urbanised Area of the Alps. [PDF]

Animals (Basel)
Böhm C, Wilberger M, Landmann A.
europepmc   +1 more source

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source

Plant biosecurity threats detected using metatranscriptomic sequencing of animal gut contents. [PDF]

Virus Evol
Mahar JE, Mifsud JCO, Van Brussel K, Lachenauer AE, Harvey E, Turnbull OMH, Bonat S, Newsome TM, Olsson A, Chiu-Werner A, Jones ME, Holmes EC, Maina S.   +12 more
europepmc   +1 more source

Material‐Induced Nuclear Deformation Controls Chromatin Architecture in Adipose Stem Cells

Advanced Science, EarlyView.
Tuning cell and cytoskeleton mechanics modulated nuclear shape and heterochromatin organization in ASCs. Distinct cytoskeletal architectures induced nuclear morphologies from oblate to prolate ellipsoids. Large elongated cells with a structured actin cap exhibited high nuclear strain, driving nuclear envelope deformation and heterochromatin ...
Carlo F. Natale, Luca Messina, Valeria Panzetta, Stefania Saporito, Costantino Menna, Maurizio Ventre, Paolo A. Netti   +6 more
wiley   +1 more source

Evaluating wildlife community composition around villages with varying Guinea worm (<i>Dracunculus medinensis)</i> transmission in Chad, Africa. [PDF]

Int J Parasitol Parasites Wildl
Korns AL, Unterwegner K, Weiss AJ, Oaukou PT, Zirimwabagabo H, Chandler RB, Morin DJ, Yabsley MJ, Cleveland CA.   +8 more
europepmc   +1 more source

BGN/MDK Axis in the Melanoma Tumor Microenvironment Strengthens Tumor Malignancy by Modulating Cancer Cells and Cancer‐Associated Fibroblasts Crosstalk

Advanced Science, EarlyView.
This study reveals that m6A regulators cooperatively upregulate BGN in melanoma, promoting malignancy. Within the tumor microenvironment, CAFs show highest BGN expression. The BGN/MDK axis mediates cancer‐stroma crosstalk, driving normal fibroblast (NF) activation and enhancing the pro‐tumor effect of CAFs, highlighting a promising therapeutic target ...
Hao‐ze Shi, Ming‐yang Wu, Jin‐quan Liu, Cuicui Tian, Li Ma, Xue‐mei Zhou, Ze‐Hao Sun, Zhi‐yong Xu, Run‐dong Zhang, Shan‐yuan Ye, Li‐ming Huang, Yan Wang, Jing‐shu Xiong, Wen‐bo Bu, Xian‐feng Cheng, Jian‐fang Sun, Hao Chen   +16 more
wiley   +1 more source

Euro-Asian hybrids of Echinococcus multilocularis from red foxes in northern and northeastern Poland result from secondary contact between long-isolated populations. [PDF]

Sci Rep
Gładysz P, Bielińska-Wąż D, Wąż P, Samorek-Pieróg M, Karamon J, Lass A.   +5 more
europepmc   +1 more source

Analysis of hyperspectral imagery for macroalgae and eelgrass mapping [PDF]

, 2009
Sandown Conservation Commission
core   +1 more source

Phase Separation of NFIB Suppresses SLC3A2‐Mediated Ferroptosis in Castration‐Resistant Prostate Cancer

Advanced Science, EarlyView.
Castration‐resistant prostate cancer (CRPC) remains sensitive to ferroptosis, but its intrinsic resistance is poorly understood. Here, we identify NFIB as a master suppressor. SIRT7‐mediated NFIB acetylation drives its liquid–liquid phase separation, which promotes SLC3A2 transcription to inhibit ferroptosis.
Qiunuo Li, Danyang Chen, Yongzhen Xia, Yili Long, Nan Huang, Rongna Li, Mengting Shi, Mairehaba Kadier, Huafeng Luo, Xiaohui Chen, Hao Liu, Guanmin Jiang   +11 more
wiley   +1 more source

Gelatinase regulates the egress of intracellular replicating populations during Enterococcus faecalis infection. [PDF]

PLoS Pathog
Tanoto FR, Liew JH, Stocks CJ, Rawat D, Chong KKL, Pethe K, Antypas H, Kline KA.   +7 more
europepmc   +1 more source