Results 211 to 220 of about 231,839 (268)

Cohort‐Scale Spatial Autocorrelation for Tumor Prediction in Mid‐Infrared Pathology and Spatial Biomarker Discovery Using MALDI Imaging Lipidomics

open access: yesAdvanced Science, EarlyView.
Computational annotation of various tissue types in heterogeneous samples such as colorectal cancer liver metastasis (CRLM) using spatial autocorrelation analysis on non‐destructive mid‐infrared (MIR) imaging data enabled correlative multimodal mass spectrometry imaging (MSI) for spatial investigation of lipid tumor marker candidates. The method can be
Miriam F. Rittel   +12 more
wiley   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto   +20 more
wiley   +1 more source

The Dynamic Energy Band Model of Contact‐Separation and Sliding Mode Triboelectric Charging of Polymers at the Metal‐Polymer Interface

open access: yesAdvanced Science, EarlyView.
Triboelectric charge generation at polymer‐metal interfaces arises from the interplay of intra‐ and inter transformation reactions of mechanochemically generated species, physical properties of polymers, environmental conditions. The direction and the magnitude of electron transfer between metal and polymer are dynamically governed by the relative ...
Sunay Dilara Ekim   +4 more
wiley   +1 more source

Respiratory‐Limbic Coupling via a Thalamic Circuit Alleviates Anxiety

open access: yesAdvanced Science, EarlyView.
This study delineates a conserved preBötCGlu→PVT→CeA circuit that gates anxiety and respiration. Activation of this circuit is anxiolytic and respiratory‐stabilizing, while its inhibition has the opposite effect. Mechanistically, PVT exerts its anxiolytic action via a disinhibitory microcircuit: its inputs preferentially target CeL GABAergic neurons ...
Shangyu Bi   +15 more
wiley   +1 more source

APEX2 proximity labeling of RNA in bacteria. [PDF]

open access: yesCell Rep Methods
Yassine H   +6 more
europepmc   +1 more source

Asymmetric Active Center Triggers Side‐On Photo‐Fenton‐Like Reaction Through Polar Charge Transfer and Self‐Adapting Sulfur Vacancies

open access: yesAdvanced Science, EarlyView.
The Cu‐Zn3In2S6 photocatalyst (Cu‐ZISV) with asymmetric Cu‐SV‐Zn sites was designed and synthesized to boost peroxymonosulfate (PMS) activation kinetics. The side‐on photo‐Fenton‐like reaction by the asymmetric Cu‐SV‐Zn site accelerated PMS activation and pollutant degradation, and the first‐order kinetic constant of Cu‐ZISV increased by 4.87 times ...
Jiaqi Hu   +7 more
wiley   +1 more source

ATRX loss couples genome instability at a G-rich repeat to dysregulation of human alpha-globin expression. [PDF]

open access: yesNat Commun
Shen Y   +8 more
europepmc   +1 more source

Unghosting the Sardinian wildcat: morphological and molecular characterization of a vanishing felid. [PDF]

open access: yesBMC Ecol Evol
Lecis R   +7 more
europepmc   +1 more source

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