Results 71 to 80 of about 75,839 (206)

Astragalus IV Undermines Multi-Drug Resistance and Glycolysis of MDA-MB-231/ADR Cell Line by Depressing hsa_circ_0001982-miR-206/miR-613 Axis

Cancer Management and Research, 2021
Hongchang Li,1,* Zhihua Xia,2,* Limin Liu,3,* Gaofeng Pan,1 Junbin Ding,1 Jiazhe Liu,1 Jie Kang,1 Jindong Li,1 Daowen Jiang,1 Weiyan Liu1 1Department of General Surgery, Institute of Fudan-Minhang Academic Health System, Minhang Hospital ...
Li H, Xia Z, Liu L, Pan G, Ding J, Liu J, Kang J, Li J, Jiang D, Liu W   +9 more
doaj  

‘Self’ and ‘othering’ as a byproduct of large‐scale assessment: An investigation into the Gaokao retake policy

British Educational Research Journal, EarlyView.
Abstract While Gaokao, the National College Entrance Examination (NCEE), has been extensively discussed outside the Chinese academic circle, the retake policy of the test has not received much attention. Moreover, Gaokao research in China has predominantly examined the effectiveness of the retake decision in relation to students' demographic ...
Yifeng Cheng, M. Obaidul Hamid
wiley   +1 more source

Minimizing Off‐Target Effects of CRISPR‐Cas9 With Optimized sgRNA: Evaluation of Efficiency and Specificity in the Tumor Protein 53 (TP53) Region

Biotechnology and Bioengineering, EarlyView.
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) – Cas9‐based genome editing has emerged as a widely used tool across various disciplines, ranging from molecular biology to gene therapy. This revolutionary technology, which enables precise gene editing, represents a significant advancement in biotechnology, opening new frontiers for ...
Ali Mertcan Köse, Monia Ranalli, Drenka Trivanovic, Irina Maslovaric   +3 more
wiley   +1 more source

The Clinicians’ Satisfaction with Clinical Pathway Implementation: Preliminary Development of an Assessment Scale in China

Risk Management and Healthcare Policy, 2021
Junlong Li,1,* Kui Shen,1,* Jun Hu,2 Xinyue Li,3 Jie Liu,1 Yonghong Du,1 Kang Huang4 1Sichuan Vocational College of Health and Rehabilitation, Zigong, Sichuan, People’s Republic of China; 2Health Information Center of Zigong, Sichuan, People&rsquo ...
Li J, Shen K, Hu J, Li X, Liu J, Du Y, Huang K   +6 more
doaj  

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

A Case of Follicular Atresia Triad Combined with Necrotising Fasciitis and Squamous Carcinoma of the Lower Limbs

Clinical, Cosmetic and Investigational Dermatology
Jinfeng Ai,1 Yihan Sun,2 Minrong Yan,1 Maolin Liu,1 Dongjun Zhong,1 Wei He,2 Xu Kang,2 Xinsheng Chen2 1The Second Clinical Medical College, Guangzhou University of Traditional Chinese Medicine, Guangzhou, People’s Republic of China; 2Dermatology ...
Ai J, Sun Y, Yan M, Liu M, Zhong D, He W, Kang X, Chen X   +7 more
doaj  

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Pt‐TiO2 mesoporous nanosystem co‐delivering phlorezin enables synergistic sonodynamic‐chemoimmunotherapy for hepatocellular carcinoma via directly targeting DDX5 and metabolic reprogramming modulation

BMEMat, EarlyView.
Abstract Hepatocellular carcinoma (HCC), ranking as the third leading cause of cancer‐related mortality globally, continues to pose significant therapeutic challenges. Here, we developed an innovative nanosystem, Phl@PT, based on Pt‐TiO2 nanoparticles for the co‐delivery of Phlorezin, presenting a novel approach for HCC treatment through sonodynamic ...
Kairui Liu, Bo Zhang, Yue Wan, Zhiru Yang, Abdusami Abdurahman, Mengxin He, Shengtao Hu, Yi Zhang, Xiaoke Li, Jin Chang, Jun Kang, Liren Liu, Wanghua Liu, Shao Li   +13 more
wiley   +1 more source

A roadmap to key traits of invasive Drosophilidae

Biological Reviews, EarlyView.
ABSTRACT Biological invasions have intensified in recent decades, mostly driven by international trade and travel, raising significant concerns, particularly regarding insect pests. Once non‐native species establish, they can disrupt natural ecosystem stability, undermine agroecosystem sustainability and cause substantial economic losses.
Gwenaëlle Deconninck, Bréa Raynaud‐Berton, Méghan Boulembert, Olivier Chabrerie, Aude Couty, Franck Dedeine, Patrice Eslin, Vincent Foray, Romain Georges, Patricia Gibert, Laurence Mouton, Sylvain Pincebourde, David Renault, Christelle Suppo, Hervé Colinet   +14 more
wiley   +1 more source

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

Biological Reviews, EarlyView.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke, Søren B. Hansen, Morten T. Limborg   +2 more
wiley   +1 more source