Results 111 to 120 of about 2,226 (262)

Multi‐Stimuli‐Responsive Hydrogen‐Bonded Organic Frameworks Nanocarriers Enable Targeted Fungicide Release and Plant Immune Regulation

Advanced Science, EarlyView.
A fluorinated hydrogen‐bonded organic framework nanocarrier (PFC‐1‐F) loaded with PYR and coated with HACC enables multi‐stimuli‐responsive (enzyme/ROS/pH) release at infection sites. Exhibiting targeted antifungal activity against Sclerotium rolfsii, modulating plant antioxidant defense, and demonstrating favorable biosafety across plant, soil, and ...
Guangming Ma, Ying Zou, Yao Wang, Huiyan Li, Jinlin Li, Tianfu Liu, Xiaohong Pan   +6 more
wiley   +1 more source

De Novo Design of Membrane‐Targeting Antimicrobial Peptides Against Gram‐Negative Bacteria Using a Generative Artificial Intelligence Framework

Advanced Science, EarlyView.
Antimicrobial resistance caused by Gram‐negative bacteria remains difficult to overcome due to the protective outer membrane. To address this challenge, a multi‐condition constrained generative AI framework, GenMTAMP is proposed for de novo membrane‐targeting antimicrobial peptide design by integrating physicochemical and spatial structure descriptors.
Jingxiao Yu, Da‐Wen Sun, QingYi Wei, Yibing Zhang, Jidong Tang, Hongbin Pu   +5 more
wiley   +1 more source

Research on assessment methods and practical analysis of livable communities in Chongqing from an urban renewal perspective. [PDF]

Sci Rep
Ma C, Yang J, Li Z, Yuan S.
europepmc   +1 more source

Electrical‐Stimulation Hydrogel Electronic Skin for Sustainable Hybrid Biomechanical–Electromagnetic Energy Harvesting and Accelerating Wound Healing

Advanced Science, EarlyView.
A hybrid biomechanical–electromagnetic energy‐harvesting e‐skin is developed using a gelatin‐based outer matrix with a zwitterionic conductive inner layer. The e‐skin autonomously generates stable electrical stimulation from daily body motion and ambient electronics, enabling significantly enhanced wound healing bothin vitro and in vivo.
Syun‐Hong Chou, Ming‐Han Lu, Wei‐Chen Peng, Wei‐Chun Yang, Pei‐Yi Liu, Yu‐Hsuan Yang, Yi‐Lin Huang, Cheng‐Hung Tsai, Ting‐Yu Yang, Xuan Zhang, Zhi‐Xian Yan, Ying‐Chih Lai, San‐Yuan Chen   +12 more
wiley   +1 more source

Whose city is it? Mapping perceived urban livability with citizen-guided AI. [PDF]

NPJ Urban Sustain
Campomanes V F, Abascal A, Oliveira LT, Kuffer M, Dijkstra AM, Stein A, Belgiu M.   +6 more
europepmc   +1 more source

Inside‐Outside ROS Therapeutic Strategy Based on Piezoelectric Nano‐Urchin for Drug‐Resistant Bacteria Biofilm Infections

Advanced Science, EarlyView.
The contribution of this study lies not only in enabling effective treatment of drug‐resistant biofilm infections, but also in establishing a transferable therapeutic paradigm: Ultrasound‐triggered mechanical forces synergistically enhance piezoelectric polarization and nanozyme activity, driving functional ROS generation inside and outside biofilms ...
Xinjian Guo, Jin Yang, Mengjie An, Bingjie Lin, Tao Liu, Limin Zhang   +5 more
wiley   +1 more source

Evaluating select factors and mechanisms influencing meat consumption in Baltimore City: an agent-based modeling study. [PDF]

BMC Public Health
Misiaszek C, Lin G, Harding J, Altema-Johnson D, Mui Y, Chang K, Bassarab K, Clancy K, Palmer A, Adam A, Ramsing R.   +10 more
europepmc   +1 more source

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng, Tristan Juin Han Chang, Xinchao Li, Zhongqi Zhou, Chung Tin, Kenward Vong, Pierre Karam, Pik Kwan Lo   +7 more
wiley   +1 more source

Narrating anxiety as "ordinary": digital self-healing diaries and the normalization of anxiety on Chinese social media. [PDF]

Front Psychol
He Y, Zhou X.
europepmc   +1 more source

Cholesterol Laundry of Cell Membrane and Fatty Liver by Detergent Liposomes to Improve Anti‐Cancer Drug Responsiveness of Patient Liver Tissues

Advanced Science, EarlyView.
Cholesterol‐enriched plasma membranes in hepatocellular carcinoma impede drug penetration. Cholesterol (+)‐liposomes act as membrane‐specific detergents, extracting cholesterol and reducing barrier function without cytotoxicity. Following endocytosis, cholesterol transfers from endosomes to liposomes and is metabolized in the ER.
Chansik Kim, Joo Kyung Noh, Sewoom Baek, Seung Eun Yu, Jueun Kim, Seongyo Lee, Youngji Oh, Dai Hoon Han, Seyong Chung, Hak‐Joon Sung   +9 more
wiley   +1 more source