Results 41 to 50 of about 4,764 (303)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Lembaga Lokal dan Masyarakat Dalam Pemenuhan Kebutuhan Rumah Bagi Masyarakat Berpenghasilan Rendah
Jurnal Pembangunan Wilayah dan Kota, 2013 Pekalongan City is one of the city in Indonesia who got the trust from the Ministry of People Housing to fulfill the needs of the livable housing for low incomes people through Rumah Inti Tumbuh (RIT).
Anggi Arimurty, Asnawi Manaf
doaj +1 more source
Park city leads the way of urban development and innovation in China
Journal of Environmental Engineering and Landscape Management, 2023 Cities have been the cradle of human civilization, with ongoing efforts to achieve the ideal city. Park cities prioritize “public” and “fair” principles in urban governance, emphasizing people-centered and livable spaces.
Xiaohang Bai, Sehrish Sadia
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Livable City/Unequal City: The Politics of Policy-Making in a « Creative » Boomtown
Revue Interventions Économiques, 2008 There is a tendency in contemporary North American urban policy-making to uncritically connect specific ideals of urban ‘livability’ with efforts to cater to the whims of the so-called ‘Creative Class.’ The paper engages with this tendency through an ...
Eugene J. McCann
doaj +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
How to make Rustavi Livable City
, 2020 Article discusses principles of sustainable urban development and focuses on three main concepts of urban development, based on sustainable development notions: Green City, Eco City, and Livable City.
Khutsishvili, Levan
core
How phagocytic cells kill bacteria: Lessons from a professional killer
FEBS Open Bio, EarlyView.How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source