Results 211 to 220 of about 1,671,583 (304)

Development of New Live-Attenuated Vaccine Candidates Lacking Antibody-Dependent Enhancement (ADE) Against Dengue. [PDF]

Vaccines (Basel)
Tan BEK, Tham SK, Poh CL.
europepmc   +1 more source

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

Smart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang, Haitao Xie, Guoqing Xiang, Yanhua Li, Changgui Tong, Hongyan Cui, Qixian Chen, Haidong Li, Yan Zhao   +8 more
wiley   +1 more source

Advances in research on layered double hydroxides for biomedical applications

Smart Molecules, EarlyView.
Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang, Zhiping Zhang, Zhao Wang, Hao Zhang, Yen Leng Pak, Yingying Jing, Yurong Guo, Fang Li, Xiao Wang, Quanxiang Han, Lei Yu, Xuejiao Li, Xing Gao, Jibin Song   +13 more
wiley   +1 more source

Attenuating Mutations in Usutu Virus: Towards Understanding Orthoflavivirus Virulence Determinants and Live Attenuated Vaccine Design. [PDF]

Vaccines (Basel)
Duyvestyn JM, Bredenbeek PJ, Gruters MJ, Tas A, Nelemans T, Kikkert M, van Hemert MJ.   +6 more
europepmc   +1 more source

Harnessing the nonthermal effects of ultrasound for cancer treatment: From mechanisms to applications

Smart Molecules, EarlyView.
Nonthermal ultrasound transforms acoustic energy into diverse therapeutic bioeffects through cavitation, mechanical stimulation, and physicochemical activation. This review discusses how acoustic parameters, biological mechanisms, and responsive materials interact to influence nonthermal ultrasound‐enabled cancer therapies. Mechanism‐guided engineering
Liu Wang, Huan Tang, Yue Pan, Mingle Li, Weijie Zhao, Kai Liu   +5 more
wiley   +1 more source

Sporadic Outbreaks of Avian Infectious Bronchitis Viruses Highly Similar to the S95 Live Attenuated Vaccine Strain in Japan: A Comparative Study of Ten Field Isolates and S95. [PDF]

Vaccines (Basel)
Nukui R, Takahashi M, Kato A, Oguro S, Tanahashi E, Ohmori T, Tsutsumi N.   +6 more
europepmc   +1 more source

Engineering metal‐organic framework‐based smart porous nanoplatforms for targeted therapy and theranostic applications

Smart Molecules, EarlyView.
MOFs offer high porosity and tunability for biomedical applications, especially in cancer therapy via ROS generation and targeted delivery. Though toxicity, stability, and scalability remain key clinical challenges. Drug loading in MOFs exceeds 60%–70% with controlled release behavior.
Jagabandhu Bag, Subhasis Banerjee, Sabyasachi Banerjee, Sourav De, S. K. Ashok Kumar, Yan‐Jye Shyong, Subhankar Mukhopadhyay   +6 more
wiley   +1 more source

Vaccinating against the absent: Risks of the B/Yamagata strain in the live attenuated vaccine. [PDF]

Euro Surveill
Koul PA.
europepmc   +1 more source

A New Clinical Paradigm: Stratified Gut Microbiota Interventions to Enhance Efficacy and Attenuate Toxicity of Cancer Immunotherapy

Microbiota Medicine Research, EarlyView.
Liang Zhang, Xinyu Du, Lijuan Sun, Ziyi Shi, Yongzhan Nie   +4 more
wiley   +1 more source

Local Eviction Moratoria and the Spread of COVID‐19

Southern Economic Journal, EarlyView.
ABSTRACT At different stages during the initial onset of the COVID‐19 pandemic, various US states and local municipalities enacted eviction moratoria. One of the main aims of these moratoria was to slow the spread of COVID‐19 infections. We deploy a semiparametric difference‐in‐differences approach with an event study specification to examine whether ...
Julia Hatamyar, Christopher F. Parmeter
wiley   +1 more source