Results 281 to 290 of about 91,730 (350)

Reflecting on experiences of resident redeployment during the COVID‐19 pandemic: Implications for leadership and theory beyond the crisis

Medical Education, EarlyView.
Abstract Introduction This study explored medical residents' experiences of redeployment during the COVID‐19 pandemic. With the benefit of time and reflection, this study went beyond an ‘educational deficit’ perspective on redeployment and examined these experiences to better understand enduring tensions in medical education, prepare leaders for ...
Paula Rowland, Melanie Hammond Mobilio, Meredith Giuliani, Cynthia Whitehead, Patricia Houston   +4 more
wiley   +1 more source

How Live Attenuated Vaccines Can Inform the Development of Broadly Cross-Protective Influenza Vaccines. [PDF]

J Infect Dis, 2019
Rudraraju R, Mordant F, Subbarao K.
europepmc   +1 more source

Molecular changes in agroinfiltrated leaves of Nicotiana benthamiana expressing suppressor of silencing P19 and coronavirus‐like particles

Plant Biotechnology Journal, EarlyView.
Summary The production of coronavirus disease 2019 vaccines can be achieved by transient expression of the spike (S) protein of severe acute respiratory syndrome coronavirus 2 in agroinfiltrated leaves of Nicotiana benthamiana. Relying on bacterial vector Agrobacterium tumefaciens, this process is favoured by co‐expression of viral silencing suppressor
Louis‐Philippe Hamel, Francis Poirier‐Gravel, Marie‐Ève Paré, Rachel Tardif, Marc‐André Comeau, Pierre‐Olivier Lavoie, Andréane Langlois, Marie‐Claire Goulet, Dominique Michaud, Marc‐André D'Aoust   +9 more
wiley   +1 more source

Emerging Highly Virulent Porcine Epidemic Diarrhea Virus: Molecular Mechanisms of Attenuation and Rational Design of Live Attenuated Vaccines. [PDF]

Int J Mol Sci, 2019
Hou Y, Wang Q.
europepmc   +1 more source

Structural Design and Immunogenicity of a Novel Self‐Adjuvanting Mucosal Vaccine Candidate for SARS‐CoV‐2 Expressed in Plants

Plant Biotechnology Journal, EarlyView.
ABSTRACT Mucosal vaccination for COVID‐19 to boost preexisting though insufficient systemic and local/mucosal immunity remains an attractive prospect but there are currently no licensed mucosal vaccines against this infection. Here, using a plant expression system, we developed a novel mucosal vaccine platform for respiratory viruses and demonstrated ...
Mi‐Young Kim, Andy Cano Tran, Ju Kim, Humblenoble Stembridge Ayuk, Adam Sparrow, Lorenzo Bossi, Megan Brown, Emil Joseph Vergara, Kathrin Göritzer, Elisabetta Groppelli, Tae‐Ho Kwon, Julian K. C. Ma, Yong‐Suk Jang, Rajko Reljic   +13 more
wiley   +1 more source

Safety and Efficacy of Plant‐Produced Trivalent Virus‐Like Particle Vaccine Candidate Against Bluetongue Disease

Plant Biotechnology Journal, EarlyView.
ABSTRACT Bluetongue (BT) is a non‐contagious, insect‐transmitted disease of wild and domestic ruminants caused by bluetongue virus (BTV). Effective control of BT disease relies on vaccination against prevalent or seasonal serotypes using live attenuated or inactivated vaccines.
Tendai A. M. Mlingo, Martha M. O'Kennedy, Matome Matsiela, Ntombikayise Nkomo, Peter Coetzee, Thapelo Rametse, Paidamwoyo Mutowembwa, Livio Heath, Nobalanda Mokoena   +8 more
wiley   +1 more source

Fatal Chronic Varicella‐Zoster Viral Infection in a Young Man With Chediak–Higashi Syndrome

Pediatric Dermatology, EarlyView.
ABSTRACT Chediak–Higashi syndrome (CHS) is a rare autosomal recessive primary immunodeficiency characterized by partial oculocutaneous albinism, neurologic involvement, and a predisposition to severe infections. Patients are particularly susceptible to developing hemophagocytic lymphohistiocytosis (HLH), which significantly worsens prognosis. We report
Albane Badet, Clément Pruvot, Zoé Manssens, Wadih Abou‐Chahla, Sébastien Buche   +4 more
wiley   +1 more source

Virus inactivation and skin safety studies using far‐UVC LEDs

Photochemistry and Photobiology, EarlyView.
This study uses an LED exposure system with a peak output at 233 nm to examine efficacy for inactivation of human coronavirus as well as potential health hazards for human exposure. Abstract Reducing airborne disease transmission is a public health goal.
David Welch, Manuela Buonanno, Camryn Petersen, Igor Shuryak, Thomas Filler, Neysha Lobo‐Ploch, David J. Brenner   +6 more
wiley   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Sustained impact of bivalent HPV immunisation on CIN incidence over two rounds of cervical screening

International Journal of Cancer, Volume 158, Issue 5, Page 1348-1360, 1 March 2026.
What's New? While vaccination against high‐risk HPV infection, the primary cause of cervical malignancy, has demonstrated long‐term effectiveness in clinical trials, real‐life longitudinal data are lacking. Here, the authors present linked long‐term screening data on the effectiveness of bivalent HPV vaccination with a minimum follow‐up of 54 months ...
Timothy J. Palmer, Kimberley Kavanagh, Kate Cuschieri, Ross L. Cameron, Catriona Graham, Allan Wilson, Kirsty Roy   +6 more
wiley   +1 more source