Results 291 to 300 of about 91,730 (350)
What's New? While previous studies have identified the carcinogenicity of viral agents such as HIV, the role of bacterial sexually transmitted infections in carcinogenesis remains understudied despite them similarly causing chronic inflammation.
Hina M. Qureshi +10 more
wiley +1 more source
ABSTRACT Against the backdrop of calling for nonfemale‐oriented promotion of vaccination against human papillomavirus (HPV), this study explored three potential names—“HPV Vaccine,” “Cervical Cancer Vaccine,” and “Genital Warts Vaccine”—to promote vaccination against HPV infection among heterosexual men.
Timothy K. F. Fung +2 more
wiley +1 more source
Abstract HPV vaccination reduces the risk of developing HPV‐attributable cancers, including cervical cancer. However, an attenuation of HPV vaccine impact after the implementation of HPV vaccination may occur through clinical unmasking. Clinical unmasking is a distinct and complex phenomenon that arises in the absence of clinical interventions ...
Joseph E. Tota +8 more
wiley +1 more source
Vaccination Recommendations in Patients With Atopic Dermatitis Treated With JAK Inhibitors
Inmunization and Screening Protocol for the Safe Initiation of JAK Inhibitors. ABSTRACT Atopic dermatitis therapy has undergone a revolutionary change with the introduction of Janus kinase (JAK) inhibitors. Despite their general safety profile, these immunomodulatory drugs require special precautions with respect to infection risk and vaccine ...
Mariano Ara‐Martín +5 more
wiley +1 more source
Inactivation of the Burkholderia Toxin Malleicyprol by Enzymatic Cyclopropanol Ring Opening
Burkholderia pseudomallei and Burkholderia mallei are dangerous pathogens that cause severe diseases with high mortality rates. Their virulence relies in part on malleicyprols, potent toxins containing a highly reactive cyclopropanol group. In this study, we identify BurK, a heme‐dependent oxidoreductase that neutralizes malleicyprols by enzymatically ...
Jonas Fiedler +4 more
wiley +2 more sources
Challenge Specific Modulation of Responses to Adjuvant‐Induced Innate Immune Memory
We utilised a commercially available adjuvant formulation to study the induction, maintenance, and consequences of innate immune memory. Using functional assays on bone marrow‐derived innate cells, extensive transcriptomic analysis of haematopoietic progenitors, and challenge models of spirochetal infection, nonspecific inflammation, and model antigen ...
Samuel T. Pasco +24 more
wiley +1 more source
Abstract Background The long‐term risk across severity strata of people infected with SARS‐CoV‐2 has not yet been comprehensively described. Methods Using nationwide registries, all COVID‐19 cases in Sweden with <2 vaccine doses, with and without initial hospitalization (February 1, 2020 to June 30, 2022), were identified and matched with non‐COVID ...
Martin Lindgren +10 more
wiley +1 more source
Microcondensate‐Mediated Intracellular Infusion of mRNA Across the Plasma Membrane
The delivery of mRNA without lipid nanoparticles remains challenging. FcB(L17E)3‐driven microcondensates with nucleic acids, aided by short ssDNA, enable coacervate formation, actin‐dependent cytosolic infusion, and in vivo protein expression, offering a potential platform for next‐generation mRNA therapeutics and vaccination.
Yoshimasa Kawaguchi +4 more
wiley +1 more source
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LIVE ATTENUATED VARICELLA VACCINE
Annual Review of Microbiology, 1996Varicella-zoster virus (VZV) is a ubiquitous human pathogen that causes varicella, commonly called chicken pox; establishes latency; and reactivates as herpes zoster, referred to as shingles. A live attenuated varicella vaccine, derived from the Oka strain of VZV has clinical efficacy for the prevention of varicella.
A M, Arvin, A A, Gershon
openaire +2 more sources
Live Attenuated Influenza Vaccine
2014Cold-adapted Ann Arbor based live attenuated influenza vaccine (LAIV) has been available in the USA since 2003. The vaccine is efficacious against influenza infection. Features of LAIV include: easy administration suitable for mass immunization, cross-reactivity to drifted strains for broader coverage, and establishment of herd immunity for control of ...
Hong, Jin, Kanta, Subbarao
openaire +2 more sources

