Results 51 to 60 of about 874,063 (266)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Design of control and hydraulic drive system for high-altitude live working vehicle
The Journal of Engineering, 2019 This article mainly introduces the motion control system of high-altitude live working vehicle and the design of the hydraulic drive system of the trolley.
Wei Song +3 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Path Planning Method for Live Working Robot in the Power Industry
IET Cyber-systems and RoboticsGiven the complexity of live working environments in power distribution networks, where autonomous obstacle avoidance by robots often involves numerous path nodes and low exploration efficiency, the Bidirectional Node‐Controlled Rapidly Exploring Random ...
Haoning Zhao +7 more
doaj +1 more source
Insulating protective cover for live working: main causes of rejection under laboratory conditions
ITEGAM-JETIA, 2020 Insulating covers are collective protective equipment widely used in the maintenance of energized aerial electrical networks. The insulating covers can be divided in rigid or flexible.
Ramón Gonzalez Guevara +1 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
An Insulator Fault Diagnosis Method Based on Multi-Mechanism Optimization YOLOv8
Applied SciencesAiming at the problem that insulator image backgrounds are complex and fault types are diverse, which makes it difficult for existing deep learning algorithms to achieve accurate insulator fault diagnosis, an insulator fault diagnosis method based on ...
Chuang Gong +4 more
doaj +1 more source