Results 81 to 90 of about 155,372 (290)

The conundrum of conservation agriculture and livelihoods in Southern Africa [PDF]

, 2011
Low crop productivity, food insecurity, hunger and malnutrition; inadequate farming knowledge and skills, implements and inputs are characteristic of smallholder agriculture in Southern Africa.
Nkala, P., Corbeels, M., Veldwisch, G.J.A., Corbeels, Marc, Huising, Jeoroen, Huising, J., Mango, N., Mango, Nelson, Jan Veldwisch, Gert, Nkala, Peter   +9 more
core  

Enhancing Livelihoods Fund: Final Report

, 2021
Over a quarter of the world’s population makes a living farming and working on small areas of land. These smallholder farmers contribute significantly to global food supply chains, but despite this make up a large proportion of the world&

core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Agroforestry as a pathway to climate-smart agribusiness: challenges and opportunities for smallholder farmers in developing countries

Frontiers in Sustainable Food Systems
Agroforestry systems are increasingly recognized for their potential to deliver climate-smart agriculture outcomes by integrating productivity, climate resilience, and environmental sustainability.
Getahun Kassa, Getahun Kassa
doaj   +1 more source

Spatial Dynamics of Invasive Para Grass on a Monsoonal Floodplain, Kakadu National Park, Northern Australia

Remote Sensing, 2019
African para grass (Urochloa mutica) is an invasive weed that has become prevalent across many important freshwater wetlands of the world. In northern Australia, including the World Heritage landscape of Kakadu National Park (KNP), its dense cover can ...
James Boyden, Penelope Wurm, Karen E. Joyce, Guy Boggs   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Investigating the Role of Poultry in Livelihoods and the Impact of HPAI on Livelihoods Outcomes in Africa: Evidence from Ethiopia, Ghana, Kenya and Nigeria [PDF]

In this paper we investigate the role of poultry in the livelihoods portfolios of households and the impact of supply and demand shocks that may be caused by Highly Pathogenic Avian Influenza (HPAI) on various livelihoods outcomes of households in four ...
Ayele, Gezahegne, Yakhshilikov, Yorbol, Asare-Marfo, Dorene, Okpukpara, Benjamin, Mensah-Bonsu, Akwasi, Roy, Devesh, Birol, Ekin, Ndirangu, Lydia K.   +7 more
core  

The Environmental Management Accounting Practices for Sustainable Ecological Performance in South African Commercial Real Estate

Journal of Sustainable Real Estate
The commercial real estate (CRE)’s slow progress in adopting green practices suggests the need to strengthen sustainable environmental accountability efforts.
Hlabanang J. Makofane, Huibrecht M. van der Poll, Silas Mukwarami   +2 more
doaj   +1 more source