Results 81 to 90 of about 41,757 (263)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Sustainable Use and Livelihoods Specialist Group launches its Species Use Database
Oryx, 2023 Rachel Hoffmann, Dilys Roe
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Hydropower and Livelihoods in the Mekong Basin: Reservoir Operation for Farming and Fishing Livelihoods, Optimal Livelihoods Strategies, and Simultaneous Optimization of Hydropower and Livelihood Goals [PDF]
, 2017 Hydropower construction, with the promise of providing sustainable energy, government revenue, and economic development, is surging throughout many regions of the world, especially in Asia. The hydropower dams, however, damage natural fisheries and submerge fields. As dam construction dislodges rural communities, rural development experts struggle with
openaire +1 more source
DiversityA previous analysis of diversity within the Monomorium nigrius Forel group, formally recognized as a single species, concluded that >200 species may occur in the Australian monsoonal tropics (AMT).
Alan N. Andersen, François Brassard
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Discover SustainabilityUniversal approaches to implementing environmental management accounting (EMA) have resulted in a paradigm shift in managing the physical and monetary aspects of the environment globally.
Silas Mukwarami +1 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Ecology and EvolutionAn understanding of how terrestrial mammalian predators use their environment is critical for the development of effective management and monitoring.
Georgina Neave +3 more
doaj +1 more source