Results 41 to 50 of about 298,308 (307)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Successful diagnosis of a localized liver tumor via transjugular liver biopsy after ascites hampered a percutaneous approach

Radiology Case Reports
Liver biopsy is a crucial diagnostic procedure for liver-related conditions. However, it is challenging to use in cases with substantial ascites or coagulopathy.
Shingo Hamaguchi, MD, Yuri Nakashima, MD, Minoru Dote, MD, Shinji Wada, MD, Kazuki Hashimoto, MD, Hidefumi Mimura, MD   +5 more
doaj   +1 more source

Hyaluronic acid levels predict risk of hepatic encephalopathy and liver-related death in HIV/viral hepatitis coinfected patients [PDF]

, 2013
Background: Whereas it is well established that various soluble biomarkers can predict level of liver fibrosis, their ability to predict liver-related clinical outcomes is less clearly established, in particular among HIV/viral hepatitis co-infected ...
Soriano, V, Christian Pradier, Soriano, Vincent, Amanda Mocroft, Lundgren, JD, Lars, Peters, Rockstroh, Jürgen, Pradier, Christian, LICHTNER, Miriam, Peters, L, Blackard, Jason, Lundgren, Jens D., F. e. In, Knysz, B, Pradier, C, for EuroSIDA in EuroCoord,, VULLO, Vincenzo, Karlsson, Anders, Rauch, A, Mocroft, Amanda, Peters, Lars, Andri Rauch, Kai Zilmer, Jens D Lundgren, Rauch, Andri, Lundgren, Jens D, Anders Karlsson, Rockstroh, J, Zilmer, K, Vincent Soriano, Jürgen Rockstroh, Knysz, Brygida, Jens D. Lundgren, for EuroSIDA in EuroCoord, Mocroft, A, Karlsson, A, Lars Peters, Zilmer, Kai, Brygida Knysz   +38 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Endoscopic Ultrasound-Guided Liver Biopsy (EUS-LB): An Endoscopic Solution to the Unmet Needs of Liver Tissue Acquisition and Beyond

Journal of Digestive Endoscopy
Aim and Objective Endoscopic ultrasound-guided liver biopsy (EUS-LB) is now increasingly being used across the globe as a method of liver tissue acquisition.
Shivam Khare, Anil Arora, Jijo Varghese, Ashish Kumar, Sunila Jain, Ashiesh Khandelwal, Arpita Mittal, Sunayana Misra, Shrihari Anikhindi, Mandhir Kumar, Piyush Ranjan, Praveen Sharma, Naresh Bansal, Munish Sachdeva, Suprabhat Giri, Srijaya S.   +15 more
doaj   +1 more source

The Role of Liver Biopsy in the Management of Patients with Liver Disease

Canadian Journal of Gastroenterology, 2003
The role of liver biopsy in the diagnosis and management of liver disease is a controversial issue even among hepatologists. Although most causes of elevated liver enzymes can be determined, or at least suspected, on the basis of a careful history and ...
Florence Wong
doaj   +1 more source

A Successful Living Donor Liver Transplantation Using Hepatic Iron Deposition Graft Suspected by Magnetic Resonance Imaging

Case Reports in Transplantation, 2023
Recently, magnetic resonance imaging (MRI) has been developed as a widely available and noninvasive method for detecting and evaluating hepatic iron overload.
Nobuhiko Kurata, Masato Shizuku, Kanta Jobara, Yoji Ishizu, Masatoshi Ishigami, Yasuhiro Ogura   +5 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Importance of liver biopsy findings in immunosuppression management: biopsy monitoring and working criteria for patients with operational tolerance

, 2012
Obstacles to morbidity-free long-term survival after liver transplantation (LT) include complications of immunosuppression (IS), recurrence of the original disease and malignancies, and unexplained chronic hepatitis and graft fibrosis.
Adeyi, O, Mölne, Johan,
core   +2 more sources