Results 101 to 110 of about 73,583 (263)

Surgically confirmed severe endometriosis is associated with lower risk of steatotic liver disease: Evidence of estrogen‐linked hepatic–reproductive crosstalk

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Severe surgically confirmed endometriosis was associated with a lower prevalence of steatotic liver disease than non‐severe disease. Higher estradiol levels may partly explain this inverse hepatic–reproductive association, supporting integrated gynecologic and hepatologic risk assessment.
Jung Hyun Park   +5 more
wiley   +1 more source

Zinc Finger E‐Box Binding Homeobox 1 Mediates Alcohol‐Induced Liver Disease

open access: yesiNew Medicine, EarlyView.
Alcohol intake leads to the upregulation of ZEB1, which activates the YAP‐IL‐1β/MCP‐1 pathway, resulting in the activation of liver inflammation and the induction of hepatocyte apoptosis. ABSTRACT Hepatitis resulting from alcoholic liver disease (ALD) is an important risk factor for liver cancer. It is essential to understand the role of ALD to prevent
Boyu Zhang   +5 more
wiley   +1 more source

Hepatic Encephalopathy and Age Were Assessed to Ameliorate the Underestimation of the Model for End‐Stage Liver Disease Score in Patients With Acute‐on‐Chronic Liver Failure

open access: yesiNew Medicine, EarlyView.
This study demonstrates that the model for end‐stage liver disease (MELD) score significantly underestimates 90‐day mortality in acute‐on‐chronic liver failure (ACLF) patients (AUC: 0.556) compared to non‐ACLF patients (area under the receiver operating characteristic curve [AUC]: 0.848).
Guanghou Chen   +5 more
wiley   +1 more source

Peritoneoscopy of alcoholic liver cirrhosis in comparison with non-alcoholic liver cirrhosis.

open access: yesPeritoneoscopy of alcoholic liver cirrhosis in comparison with non-alcoholic liver cirrhosis.
Peritoneoscopic findings of 39 patients with alcoholic liver cirrhosis (ALC) were compared with those of 95 patients with non-alcoholic liver cirrhosis (NALC). They were selected from 245 patients with liver cirrhosis subjected to peritoneoscopy in the 7 year period from 1975 to 1981. Out of the 95 NALC patients, 24 had hepatitis B surface antigen. The
openaire  

Mode‐of‐Action and Human Relevance Assessment for Diisononyl Phthalate‐Induced Liver Tumors in Rodents

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger   +3 more
wiley   +1 more source

Biochemical and Molecular Insights Into Monocrotaline‐Induced Hepatotoxicity: An Experimental Mouse Study

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Monocrotaline (MCT), a plant‐derived pyrrolizidine alkaloid, is well known for its hepatotoxic effects. However, full elucidation of the mechanisms underlying MCT‐induced hepatotoxicity, as well as the development of reliable biomarkers for early detection and monitoring, requires an integrated evaluation of biochemical, molecular, and ...
Ali Şenol   +4 more
wiley   +1 more source

Characteristics of Adverse Effects in Patients with Chronic Alcoholic Pancreatitis and Concomitant Alcoholic Liver Cirrhosis Child-Pugh Class A and B

open access: yesGalician Medical Journal, 2016
Alcohol intoxication is the third leading cause of death, and among alcohol-dependent patients alcohol-related pathology (alcoholic liver disease, acute and chronic pancreatitis, cardiomyopathy, polyneuro-encephalopathy) accounts for 42.6% of fatal cases.
K. M. Skoropad, V. H. Mishchuk
doaj  

Soluble B7‐H6 as a Novel Diagnostic Biomarker for Post‐Hepatitis B Cirrhosis: A Clinical Value Study

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study investigates the potential of soluble B7‐H6 (sB7‐H6) as a novel diagnostic biomarker for post‐hepatitis B cirrhosis. The infographic visually presents the following key points: (1) Liver Disease Progression: Chronic hepatitis B (CHB) progresses to liver cirrhosis (LC), with serum sB7‐H6 levels increasing stepwise as the disease advances. (2)
Kaiyong Chen   +4 more
wiley   +1 more source

Changes of CEA Diagnostic Performance Under the New Reference Interval Stratified by Age and Sex

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Our study included patients with lung cancer, breast cancer, and colorectal cancer and apparently healthy individuals, conducted a large case–control study to assess the effects of age and sex on serum concentrations and positive rates of CEA, established age‐ and sex‐stratified reference intervals using indirect methods.
Ke Zhang, Xiarui Ye
wiley   +1 more source

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