Results 171 to 180 of about 110,732 (262)

Risk Prediction of Early‐Onset Hepatocellular Carcinoma: Derivation and Validation in a Nationwide Young Adult Cohort

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In 1,756,593 young adults, a generalized boosted survival model predicted incident HCC with strong discrimination (1‐year AUROC 0.945; 5‐year 0.825). The 1‐year horizon uniquely targets an imaging‐silent, pre‐diagnosis window, showing routine clinical signals can flag otherwise undetectable risk.
Seogsong Jeong   +7 more
wiley   +1 more source

The Prevalence and Risk Factors for at‐Risk MASH and Advanced Liver Fibrosis in People With Metabolic Risk Factors in Primary Care

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
This cross‐sectional study of 84 general practices found 24.3% had At‐Risk MASH defined by FNI > 0.30, and 4.3% had advanced fibrosis defined by FIB‐4 > 2.67. Diabetes and socio‐economic disadvantage were strong predictors of significant liver disease.
Leon A. Adams   +7 more
wiley   +1 more source

Socioeconomic Inequalities in Receipt of Curative‐Intent Treatment and Survival After Surveillance‐Detected Hepatocellular Carcinoma: A Nationwide Cohort Study

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Socioeconomic inequalities in receipt of curative‐intent treatment and survival persist among individuals with surveillance‐detected HCC within a universal healthcare system. These findings suggest that surveillance alone is insufficient to ensure equitable outcomes and highlight the need for strategies addressing social determinants across the care ...
Hannes Hagström   +6 more
wiley   +1 more source

S1 Guideline on Infected Interdigital Intertrigo (also called Gram‐Negative Toe Web Infection)

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Infected interdigital intertrigo is an exudative, macerating, mixed infection of the toe webs in which gram‐negative bacteria (Pseudomonas aeruginosa and Enterobacterales) seem prevalent, but in which gram‐positive pathogens (Staphylococcus [S.] aureus, streptococci, enterococci) and fungi (dermatophytes, yeasts) also occur.
Christoph Zeyen   +10 more
wiley   +1 more source

Differential Impact of Metabolic Bariatric Surgery Versus Semaglutide on Adverse Hepatic and Extrahepatic Outcomes in Individuals With Metabolic Dysfunction‐Associated Steatotic Liver Disease and Type 2 Diabetes

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim We compared the impact of metabolic bariatric surgery (MBS) versus semaglutide on clinical outcomes in individuals with metabolic dysfunction‐associated steatotic liver disease (MASLD) and type 2 diabetes (T2D). Methods Patients with MASLD and T2D who had MBS or semaglutide in 2018–2023 were identified (TriNetX database).
Weronika Stupalkowska   +5 more
wiley   +1 more source

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