Results 121 to 130 of about 82,056 (314)

Two stable gut microbiome guilds predict liver tumor class and treatment responses

iMeta, EarlyView.
Gut microbiome alterations are linked to hepatocellular carcinoma (HCC), yet taxon‐based biomarkers often lack reproducibility. Using shotgun metagenomics from 120 resectable HCC (MT) and 76 benign hepatic tumor controls (BT), we reconstructed a stable interaction‐based Two Competing Guilds model (HCC‐TCG) comprising 142 genomes organized into two ...
Yang Liu, Zefan Zhang, Guojun Wu, Bowen Li, Linghua Wang, Jincheng Wang, Zixian Wei, Zhiyue Wang, Jinhua Yang, Kunyu Zhang, Tianqi Zhang, Xin Tao, Tao Chen, Jia Fan, Jian Zhou, Xinrong Yang, Liping Zhao, Yunwei Wei   +17 more
wiley   +1 more source

Long-term effects of human amniotic membrane in a rat model of biliary fibrosis

Brazilian Journal of Medical and Biological Research
Liver fibrosis is the most common outcome of chronic liver diseases, and its progression to cirrhosis can only be effectively treated with liver transplantation.
L.B. Sant'Anna, F.S. Brito, P.R. Barja, M.C. Nicodemo   +3 more
doaj   +1 more source

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, EarlyView.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source

Comparative Outcomes of Endoscopic Treatment for Symptomatic and Asymptomatic Common Bile Duct Stones in the Elderly: A Propensity Score‐Based Cohort Analysis

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Introduction Various guidelines recommend endoscopic stone removal for asymptomatic common bile duct stones (CBDS); however, previous studies have indicated that asymptomatic CBDS is associated with a higher incidence of post‐ERCP pancreatitis (PEP).
Kota Shimojo, Akinori Maruta, Keisuke Iwata, Yuhei Iwasa, Mitsuru Okuno, Kensaku Yoshida, Shinya Uemura, Tsuyoshi Mukai, Takuji Iwashita, Masahito Shimizu   +9 more
wiley   +1 more source

Chronic Liver Disease: Assessing Inflammation and Fibrosis Using Three‐Dimensional MR Elastography With Same‐Day Biopsy in a Prospective Cohort

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Three‐dimensional (3D) MR elastography (MRE) derives viscoelastic parameters that may reflect inflammation, but their frequency dependence and the influence of steatosis on inflammation grading and fibrosis staging remain unclear. Purpose To investigate 3D multifrequency MRE for assessing hepatic inflammation, fibrosis stage across ...
Shan Cai, Christian Simonsson, Markus Karlsson, Wile Balkhed, Jens Tellman, Simone Ignatova, Patrik Nasr, Mattias Ekstedt, Stergios Kechagias, Wolf C. Bartholomä, Nils Dahlström, Peter Lundberg   +11 more
wiley   +1 more source

Association between specialized nutrition support and 90‐day mortality relative to standard of care in malnourished adults with decompensated cirrhosis: A retrospective cohort study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Malnutrition is common among patients with decompensated liver cirrhosis and linked to poor prognosis. Guidelines recommend intensified nutrition support e.g. parenteral nutrition, but evidence regarding safety and effectiveness is scarce. We aimed to investigate the impact of nutrition support, specifically parenteral nutrition, on
Katharina L. Hupa‐Breier, Laura Buttler, Claudia Seipt, Andrea Markowski, Marie Griemsmann, Tammo L. Tergast, Birgit Kaufmann, Hannah Rieland, Heiner Wedemeyer, Benjamin Maasoumy, Andrea Schneider   +10 more
wiley   +1 more source

Serum aspartate aminotransferase to platelet ratio index in relation to liver histopathology of biliary atresia

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives To investigate the prognostic significance of aspartate aminotransferase to platelet ratio index (APRI) in relation to histopathological features across the clinical course of biliary atresia (BA). Methods In this observational cohort study, we enrolled 135 BA patients with available APRI values at Kasai portoenterostomy (KPE, n ...
Nicholas Nordenheim, Iiris Nyholm, Maria Hukkinen, Nelli Sjöblom, Aino Mutka, Jouko Lohi, Mark Davenport, Mikko P. Pakarinen   +7 more
wiley   +1 more source

Effects of intraduodenally applied bile salts on pancreatic secretion [PDF]

, 1993
Lehnert, Peter, Riepl, Rudolf L.
core   +1 more source

Serum predictors of native liver survival post‐Kasai: Systematic review and meta‐analysis

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives After hepatoportoenterostomy (HPE), a minority of biliary atresia (BA) patients reach adolescence without liver transplantation. Several serum markers have been suggested to better predict post‐HPE outcomes in BA patients. We aimed to identify serum predictors of native liver survival (NLS) in post‐HPE BA patients.
Ahmad Anouti, Hamza Dahshi, Thomas G. Cotter, Tebyan A. Rabbani, Natasha Corbitt, Sara Hassan   +5 more
wiley   +1 more source

Early Liver Retransplantation in a Pediatric Patient with Biliary Atresia and Treatment of Complications

Indian Journal of Transplantation
Pediatric liver transplantation is the main therapeutic modality for patients with liver cirrhosis secondary to biliary atresia. Unfortunately, approximately 22% will require a retransplantation.
Mauricio Alejandro Saldaña Ruiz, José Guillermo Martínez Flores, Federico Ortiz Alonso, Liliana Sayuri Tapia Brito   +3 more
doaj   +1 more source