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Liver Transplantation for Primary Biliary Cirrhosis

2014
Primary biliary cirrhosis (PBC) is one of the most common indications for adult liver transplantation in both Western countries and Japan. Recently, the number of liver transplantations for PBC has shown a decreasing trend in Europe and the United States, likely due to advances in medical therapies using ursodeoxycholic acid.
Takuya, Genda, Takafumi, Ichida
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Primary Biliary Cirrhosis and Liver Transplantation

New England Journal of Medicine, 1982
Primary biliary cirrhosis is a chronic liver disease of unknown cause that predominantly affects middleaged women.1 The syndrome of primary biliary cirrhosis arises as a consequence of a chronic nonsuppurative destructive cholangitis that involves the septal and larger interlobular bile ducts.2 The rate at which the bile-duct lesions evolve varies and ...
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[Primary biliary liver cirrhosis].

Acta medica Austriaca, 1983
Primary biliary cirrhosis, or chronic destructive nonsuppurative cholangitis, is a condition of chronic cholestasis, in which small intrahepatic bile ducts in the portal zones of the liver become progressively destroyed. The etiology of primary biliary cirrhosis is unknown, but the observation of (a) mitochondrial antibody, (b) elevated serum levels of
S, Sailer, G, Lanzer
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PROGNOSIS AFTER LIVER TRANSPLANTATION FOR PRIMARY BILIARY CIRRHOSIS

Transplantation, 1989
Timing of transplantation for patients with primary biliary cirrhosis (PBC) requires identification not only of individual risk factors for the operation but estimation of survival with and without transplantation. To identify those risk factors and develop a prognostic model, 82 patients grafted for PBC since 1980 in the Birmingham and Cambridge/King ...
J, Neuberger   +8 more
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Recurrence of Primary Biliary Cirrhosis after Liver Transplantation

New England Journal of Medicine, 1982
Three patients who had undergone orthrotopic liver transplantation for primary biliary cirrhosis and were being maintained on immunosuppressive therapy were investigated 31/2 to 41/2 years later because of the redevelopment of pruritus and mild jaundice.
J, Neuberger   +4 more
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Primary liver lymphoma associated with primary biliary cirrhosis

Histopathology, 1993
We describe a case of a primary polymorphic centroblastic–centrocytic B‐cell lymphoma of the liver developing in a patient with primary biliary cirrhosis—an association which has not previously been reported.We would like to thank Dr C.Fisher, Department of Histopathology, The Royal Marsden Hospital, Fulham Road, London.
R, Goldin   +4 more
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Liver schistosomiasis and primary biliary cirrhosis

Virchows Archiv A Pathological Anatomy and Histology, 1974
The case of a patient suffering from liver schistosomiasis diagnosed by liver biopsies is presented. There were also lesions in the liver suggestive of non-suppurative destructive cholangitis and the serum-immunological studies strengthened the diagnosis of primary biliary cirrhosis.
S, Berthoud   +3 more
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[Morphogenesis of primary biliary liver cirrhosis].

Arkhiv patologii, 1988
Light and electron microscopy were employed for evaluation of hepatic biopsies (9 puncture and 3 operative) to study morphologic changes in small bile ducts and lobular parenchyma in primary biliary cirrhosis (PBC). Altogether 12 female patients with PBC stage I and II and aged 36-59 were examined.
N V, Popova   +3 more
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[Primary biliary cirrhosis of the liver].

Arkhiv patologii, 1986
Primary biliary cirrhosis (PBC) of the liver is considered to be an autoimmune liver disease in which an immune aggression is directed against small biliary ducts--mitochondrial antigens of a biliary epithelium. The targets of an immune aggression in PBC may also be the histocompatibility antigens of the biliary ducts epithelium.
M S, Popov, I V, Popova
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[Liver transplantation for primary biliary cirrhosis].

Schweizerische medizinische Wochenschrift, 1992
Primary biliary cirrhosis (PBC) is regarded as one of the optimal indications for orthotopic liver transplantation (OLT) in adults. Between July 1987 and August 1991, 7 patients had PBC as the indication for OLT. 6 were transplanted and one patient is still on the waiting list.
G, Mentha   +8 more
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