Magnetic Resonance Elastography and Portal Hypertension: Influence of the Portal Venous Flow on the Liver Stiffness [PDF]
Stem Cells and Regenerative Medicine -- the 9th International
Europe-China Symposium, Strasbourg 2-4 Oct 2019, In press, 2020 The invasive measurement of the hepatic venous pressure gradient is still considered as the reference method to assess the severity of portal hypertension. Even though previous studies have shown that the liver stiffness measured by elastography could predict portal hypertension in patients with chronic liver disease, the mechanisms behind remain today
arxiv
COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING LIVER CIRRHOSIS [PDF]
, 2006 This invention provides a method for treating liver cirrhosis in a subject comprising administering to the subject a therapeutically effective amount of a rAAV/CAG-STAP vector, to treat liver cirrhosis in the subject.
core
The Royal Free Hospital score: a calibrated prognostic model for patients with cirrhosis admitted to intensive care unit. Comparison with current models and CLIF-SOFA score [PDF]
, 2014 Prognosis for patients with cirrhosis admitted to intensive care unit (ICU) is poor. ICU prognostic models are more accurate than liver-specific models.
Agarwal, B +6 more
core +1 more source
Advanced Science, EarlyView.The study reveals that glutaminolysis in macrophages is inhibited under type 2 diabetes mellitus (T2DM) conditions, which impedes fracture healing by reducing bone morphogenetic protein 2 (BMP2) production through increased cytosine methylation on the promoter.
Jing Wang +12 more
wiley +1 more source
TGF-β1 Induces the Dual Regulation of Hepatic Progenitor Cells with Both Anti- and Proliver Fibrosis
Stem Cells International, 2016 Transforming growth factor-beta 1 (TGF-β1) plays a central role in hepatic progenitor cells- (HPCs-) mediated liver repair and fibrosis. However, different effects of TGF-β1 on progenitor cells have not been described.
Ai-Ting Yang +9 more
doaj +1 more source
Pemodelan Deteksi Penyakit Sirosis Hati dengan Menggunakan Jaringan Syaraf Tiruan [PDF]
, 2012 Liver (liver) is the largest organ in the human body. In the hearts of many important processes occur in human life. Unfortunately, although the liver is essential for life, the liver is also susceptible to disease.
H, M. E. (Marselina) +2 more
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Impact of previous hepatitis B infection on the clinical outcomes from chronic hepatitis C? A population-level analysis [PDF]
, 2018 Chronic coinfection with hepatitis C virus (HCV) and hepatitis B virus (HBV) is associated with adverse liver outcomes. The clinical impact of previous HBV infection on liver disease in HCV infection is unknown. We aimed at determining any association of
Allen, S. +20 more
core +4 more sources
Advanced Science, EarlyView.Aided by FABP5, abnormally elevated asprosin in hepatocytes enters the nucleus, targets and inhibits PPARα binding to the CPT1A promoter, thereby suppressing FAO. Circulating asprosin exacerbates insulin resistance, collectively driving MASLD progression.
Yuan‐Yuan Yu +13 more
wiley +1 more source
Beta-blockers and physical frailty in patients with end-stage liver disease. [PDF]
, 2018 AimTo investigate beta-blocker (BB) use in patients with cirrhosis and determine their effects on physical frailty and overall survival.MethodsAdult outpatients with cirrhosis listed for liver transplantation underwent testing of physical frailty using ...
Hayssen, Hilary +3 more
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Gelsolin's Protective Role in MASH through F‐Actin Regulation and P53 Degradation
Advanced Science, EarlyView.Gelsolin (GSN) maintains liver metabolic homeostasis by promoting MDM2‐mediated P53 degradation and inhibiting F‐actin/Yes‐associated protein (YAP) overactivation. Loss of GSN impairs P53 degradation, increases lipid deposition, and enhances YAP‐driven fibrosis and inflammation in metabolic‐associated steatohepatitis.
Yiwei Lu +9 more
wiley +1 more source