Results 101 to 110 of about 2,061,642 (403)
Advanced Science, EarlyView.The study found that RPL6 is frequently upregulated in HCC tissues with extrahepatic metastasis. Elevated RPL6 bound to and increased the stability of HMGCS1 mRNA, thereby enhancing intracellular cholesterol levels. Subsequently, increased cholesterol promotes cancer metastasis in HCC by stabilizing HIF‐1α protein.
Minli Yang +15 more
wiley +1 more source
Diagnostics, 2023 Atrial fibrillation is frequently diagnosed in patients with liver cirrhosis, especially in those with non-alcoholic steatohepatitis or alcoholic etiology.
Irina Gîrleanu +16 more
doaj +1 more source
Beta-blockers and physical frailty in patients with end-stage liver disease. [PDF]
, 2018 AimTo investigate beta-blocker (BB) use in patients with cirrhosis and determine their effects on physical frailty and overall survival.MethodsAdult outpatients with cirrhosis listed for liver transplantation underwent testing of physical frailty using ...
Hayssen, Hilary +3 more
core
Advanced Science, EarlyView.Plant‐derived bioactive molecules with low solubility and permeability induce hepatocyte injury, though the mechanisms driving their hepatic effects remain poorly understood. This study identifies a novel transport pathway in which poorly soluble indirubin accumulates in the liver via macrophage‐mediated uptake in Peyer's patches, exacerbating hepatic ...
Yiqi Xu +9 more
wiley +1 more source
Liver transplantation for viral hepatitis in 2015 [PDF]
, 2016 Liver transplantation (LT) is a life-saving treatment for patients with end-stage liver disease and for patients with liver cell cancer related to liver disease.
Bortoluzzi, Ilaria +8 more
core +1 more source
ON THE TREATMENT OF CIRRHOSIS OF THE LIVER. [PDF]
JAMA: The Journal of the American Medical Association, 1901 Cirrhosis of the liver—often called alcoholic cirrhosis —is seen under the following circumstances: 1, without symptoms, the patient having died from other causes; 2, without symptoms until a climax is reached in the sudden outbreak of gastric or intestinal hemorrhage, terminating the life of the patient; 3, with symptoms due to obstruction of the ...
openaire +3 more sources
International Journal of Molecular Sciences, 2018 Cirrhosis is a form of liver fibrosis resulting from chronic hepatitis and caused by various liver diseases, including viral hepatitis, alcoholic liver damage, nonalcoholic steatohepatitis, and autoimmune liver disease.
K. Nishikawa, Y. Osawa, K. Kimura
semanticscholar +1 more source
Advanced Science, EarlyView.ENTPD5‐mediated conversion of extracellular adenosine triphosphate to ADP of hepatocytes is critical for maintaining hepatic glucose/lipid metabolism and promoting brown adipose tissue thermogenesis via the inhibition of adrenomedullin expression and secretion.
Rufeng Ma +9 more
wiley +1 more source
Experimental and Therapeutic Medicine, 2019 The accumulation of toxic bile acids (BAs) is closely related to liver injury, inflammation and tumorigenesis. The aim of the present study was to determine the role of the serum BA spectrum in the diagnosis and progression of liver cirrhosis. This was a
Ning Liu +7 more
semanticscholar +1 more source
Advanced Science, EarlyView.Macrophage GHSR‐Foxo1 axis regulates CCl4‐induced liver fibrosis by promoting inflammation and TGF‐β1‐mediated HSC activation. GHSR activates PKA‐dependent phosphorylation of Foxo1 at serine 273, promoting macrophage pro‐inflammatory polarization to enhance the production of pro‐inflammatory cytokines that damage hepatocytes, thereby inducing liver ...
Da Mi Kim +9 more
wiley +1 more source