Results 171 to 180 of about 2,052,006 (381)
ABSTRACT Gaucher disease (GD) is a rare lysosomal storage disorder characterized by multisystemic involvement. With the advent of enzyme replacement therapy (ERT), patient survival has improved, revealing new long‐term complications. We report a case of a 4‐year‐old male with severe neurovisceral GD who developed protein‐losing enteropathy (PLE ...
Vincenza Gragnaniello+7 more
wiley +1 more source
IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases Abstract Background and Aims Pruritus is associated with multiple liver diseases, particularly those with cholestasis, but the mechanism remains incompletely understood.
Jun Xu+20 more
wiley +1 more source
Association of biochemical, cytokine and echocardiographic markers of cardiovascular injuries with t894g polymorphism of endothelial nitric oxide synthase gene in patients with nonviral liver cirrhosis [PDF]
Background & Aims: Alterations of vascular endothelium play an important role in the development of cardiovascular diseases, the occurrence of liver cirrhosis and the progression of its complications.
Taras Boychuk, Vasyl Prysyazhnyuk, Olexander Voloshyn, Larysa Sydorchuk, Roman Bulyk
core
Cirrhosis of the Liver and Icterus of Four Years' Duration: With Remarks on Biliary Cirrhosis [PDF]
F. P. Weber
openalex +1 more source
Contemporary Epidemiology of Chronic Liver Disease and Cirrhosis.
A. Moon, A. Singal, E. Tapper
semanticscholar +1 more source
Therapeutic targeting of myeloid cells in liver fibrosis: Mechanisms and clinical prospects
This review systematically summarizes the origin, recruitment, and differentiation regulation mechanisms of myeloid cells in driving hepatic fibrosis progression. By targeting these three critical phases, potential therapeutic strategies for liver fibrosis can be explored.
Yue Wang+5 more
wiley +1 more source
Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis
EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu+16 more
wiley +1 more source
Remarks ON THE OPERATIVE CURE OF ASCITES DUE TO LIVER CIRRHOSIS [PDF]
Rutherford Morison
openalex +1 more source
Abstract Plutonium was discovered and first synthesized in the early 1940's. Several isotopes of plutonium are used in nuclear technologies, 238Pu for heat generation and 239Pu for energy production and weapons. Both isotopes emit alpha particles, which pose a significant radiation hazard when incorporated into the body.
Scott C. Miller
wiley +1 more source
Abstract Background and Aims Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.
Vineesh Indira Chandran+17 more
wiley +1 more source