Results 321 to 330 of about 2,061,642 (403)

Saliva as a TDM matrix and its application in the model‐informed precision dosing

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract This study reviews the main points of saliva as a therapeutic drug monitoring (TDM) matrix, its advantages and limitations, the methods of saliva sample collection and testing, the types of drugs in saliva TDM, and the methods of establishing saliva population pharmacokinetic (Pop PK) models, as well as summarizes the experiences and ...
Baohua Xu   +9 more
wiley   +1 more source

Noninvasive Evaluation of Prolonged-Release Pirfenidone in Compensated Liver Cirrhosis. ODISEA Study, a Randomised Trial. [PDF]

open access: yesLiver Int
Muñoz-Espinosa LE   +17 more
europepmc   +1 more source

Application of Two‐Dimensional Shear Wave Elastography in Evaluating Liver Reserve Function in Patients With Liver Cancer

open access: yesJournal of Clinical Ultrasound, EarlyView.
ABSTRACT Background Shear wave elastography (SWE) is an emerging noninvasive imaging technique for assessing liver fibrosis. This meta‐analysis aimed to evaluate the diagnostic accuracy of SWE compared to conventional imaging techniques. Methods A systematic search was conducted in PubMed, Embase, Cochrane Library, and Web of Science databases.
Bijuan Hu, Zhiping Huang, Liyin Huang
wiley   +1 more source

Outcomes of Patients With Unresectable Cholangiocarcinoma After Portal Vein Embolization: A Propensity Score‐Matched Analysis

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background This study aimed to evaluate the outcomes of patients with unresectable cholangiocarcinoma (CCA) who underwent portal vein embolization (PVE) with a focus on overall survival (OS) and the frequency of biliary drainage (BD). Methods In this retrospective analysis, we evaluated 255 patients with unresectable CCA; 56 patients underwent
Ho Seung Lee   +8 more
wiley   +1 more source

Preoperative Multifrequency MR Elastography for Stratifying Wnt/β‐Catenin Pathway and Microvascular Invasion Phenotypes in Hepatocellular Carcinoma

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background The Wnt/β‐catenin signaling pathway and microvascular invasion (MVI) are associated with the prognosis of hepatocellular carcinoma (HCC). Purpose To evaluate the Wnt/β‐catenin pathway and MVI states using preoperative MR elastography (MRE). Study Type Prospective.
Huanhuan Chong   +9 more
wiley   +1 more source

Which liver-disease patients need a transplant? [PDF]

open access: yes, 1988
Gordon, RD   +13 more
core  

Motion‐Insensitive Flip Angle Modulated Liver Proton Density Fat‐Fraction and R2* Mapping During Free‐Breathing MRI in a Clinical Setting

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Breath‐held quantitative three‐dimensional chemical‐shift‐encoded (3D‐CSE)‐MRI is widely used for liver fat and iron quantification but is limited in patients unable to hold breath. Motion‐insensitive two‐dimensional flip angle modulated (2D‐FAM) acquisitions with short temporal aperture may address this limitation.
Julius F. Heidenreich   +9 more
wiley   +1 more source

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