Results 91 to 100 of about 2,535,651 (215)

Endocannabinoid receptor blockade increases hepatocyte growth factor and reduces insulin levels in obese women with polycystic ovary syndrome [PDF]

open access: yes, 2016
There is evidence from animal and in-vitro studies that activation of the endocannabinoid system (EC) through cannabinoid receptor 1 (CB-1) is associated with liver injury, inflammation and hepatocellular carcinoma.1 Data suggests endogenous cannabinoids
Ahmed, Lina   +6 more
core   +2 more sources

Matrix metalloproteinases in liver injury, repair and fibrosis. [PDF]

open access: yes, 2015
The liver is a large highly vascularized organ with a central function in metabolic homeostasis, detoxification, and immunity. Due to its roles, the liver is frequently exposed to various insults which can cause cell death and hepatic dysfunction ...
Baber, John   +3 more
core   +1 more source

Transarterial Chemoembolization Combined with Regorafenib and PD-1 Inhibitor as Second-Line Therapy for Unresectable Hepatocellular Carcinoma

open access: yesCancer Management and Research
Di Wang,1,* Wei Zhang,2,* Xudong Gao,2 Huifang Kong,2 Huixin Zhang,2 Jiagan Huang,2 Meng Zhang,1 Xiujuan Chang,2 Zhen Zeng1,2 1 302 Clinical Medical School, Peking University, Beijing, People’s Republic of China; 2Senior Department of ...
Wang D   +8 more
doaj  

Plasma galectin-3 can be considered as a non-invasive marker to predict the prognosis of ACLF patients with new typing

open access: yesScientific Reports
Very recently, we creatively put forward a new classification for ACLF patients, which lays the foundation for the establishment of prognostic model that can accurately predict the prognosis of ACLF patients.
Li Bai   +5 more
doaj   +1 more source

Expression and function of osteopontin variants in HCV-related liver disease and hepatocellular carcinoma. [PDF]

open access: yes, 2010
Osteopontin (OPN) is a highly secreted multi-functional sialoprotein that is widely expressed in tissues, blood and urine. It is involved in a number of normal physiological functions, but is also significantly elevated in a number of cancers.
Phillips, Renee Jade
core   +1 more source

Peg-IFNα combined with hepatitis B vaccination contributes to HBsAg seroconversion and improved immune function

open access: yesVirology Journal
Purpose The purpose of this study was to investigate immunological variations between a group that received the hepatitis B vaccine and a non-vaccine group. We focused on a cohort that achieved HBsAg seroclearance after Peg-IFNα treatment of CHB. Methods
Yisi Liu   +9 more
doaj   +1 more source

Evidence construction of Silibinin capsules against alcoholic liver disease based on a meta-analysis and systematic review

open access: yesFrontiers in Pharmacology
BackgroundIn recent years, the incidence of alcoholic liver disease (ALD) has rapidly increased worldwide, becoming a significant health issue. Silibinin capsules have shown potential in treating ALD, but clinical evidence is still insufficient.
Yan Wang   +24 more
doaj   +1 more source

Hepatitis B virus-infected hepatocytes promote the secretion of collagen VI to the extracellular matrix

open access: yesScientific Reports
Chronic hepatitis B virus (HBV) infection is a global health problem as it is the major cause of liver fibrosis and its complications cirrhosis and hepatocellular carcinoma.
Alessia Virzì   +18 more
doaj   +1 more source

CyTOF reveals platelet subtype changes predicting the efficacy of combined immunotherapy and targeted therapy in liver cancer

open access: yesFrontiers in Immunology
IntroductionImmune checkpoint inhibitors combined with angiogenesis inhibitors are currently the first-line treatment for liver cancer. However, some patients still exhibit poor therapeutic outcomes.
Wenjing Wang   +7 more
doaj   +1 more source

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