Results 41 to 50 of about 2,453,090 (361)

Droxinostat, a Histone Deacetylase Inhibitor, Induces Apoptosis in Hepatocellular Carcinoma Cell Lines via Activation of the Mitochondrial Pathway and Downregulation of FLIP

Translational Oncology, 2016
Background: The current chemotherapeutic outcomes for hepatocellular carcinoma (HCC) are not encouraging, and long-term survival of this patient group remains poor.
Jing Liu, Guangming Li, Xiang Wang, Liang Wang, Rui Zhao, Juanxia Wang, Yin Kong, Jie Ding, Juan Li, Lingyi Zhang   +9 more
doaj   +1 more source

Intestinal transplantation in children under FK 506 immunosuppression [PDF]

, 1993
Intestinal transplantation, solitary (n = 3) or in combination with the liver (n = 7), was performed in 10 pediatric patients with intestinal failure. The liver was only replaced if there was liver failure and portal hypertension.
Adrian Casavilla, Andreas G. Tzakis, Anthony J. Demetris, Bakr Nour, David H. Van Thiel, Eduardo Yunis, Goulet, Grant, Iwaki, Jorge Reyes, Kareem Abu-Elmagd, Murase, Murase, Rick Selby, Samuel Kocoshis, Satoru Todo, Schraut, Shaffer, Starzl, Starzl, Starzl, Thomas E. Starzl, Todo, Todo, Tzakis, Tzakis, Zhong   +26 more
core   +1 more source

Housing-temperature reveals energy intake counter-balances energy expenditure in normal-weight, but not diet-induced obese, male mice

Communications Biology, 2022
The impact of ambient housing temperature on the interaction of energy intake, energy expenditure and glycemic control in normal and diet-induced obese mice is examined.
Linu Mary John, Natalia Petersen, Marina Kjærgaard Gerstenberg, Lola Torz, Kent Pedersen, Berit Østergaard Christoffersen, Rune Ehrenreich Kuhre   +6 more
doaj   +1 more source

Study on the Retreatment, Outcome, and Potential Predictors of Recurrence in Patients With Recurrence of Hepatitis B After Functional Cure

Frontiers in Immunology, 2022
BackgroundStudies about the retreatment and predictors for patients with hepatitis B recurrence after functional cure are rare. This study aimed to evaluate the effect of retreatment, outcome, and potential predictors of recurrence in patients with ...
Xiao Lin, Aixin Song, Junfeng Lu, Sujun Zheng, Zhongjie Hu, Lina Ma, Zhenhuan Cao, Hong Li, Yanhong Zheng, Shan Ren, Xinyue Chen   +10 more
doaj   +1 more source

Open and / or laparoscopic surgical treatment of liver hydatic cysts [PDF]

, 2018
Hydatid disease is a severe parasitic disease with a widely ranging distribution. In the human being the liver is the most frequent organ affected. 1 The treatment should be individualized to the morphology, size, number and location of the cysts, that ...
Al Karowda‘a E. A., Codacci Pisanelli M., De Toma G., D’Andrea V., Izzo L., Izzo P., Izzo R., Izzo S., Messineo D., Pugliese F.   +9 more
core   +1 more source

Serum hepatitis B virus large and medium surface proteins as novel tools for predicting HBsAg clearance

Frontiers in Immunology, 2022
BackgroundThere is still lack of reliable predictors for hepatitis B surface antigen (HBsAg) clearance. Recent studies have shown that the levels of large (LHBs) and medium hepatitis B surface proteins (MHBs) are closely related to antiviral efficacy ...
Xiao Lin, Yanhong Zheng, Hong Li, Junfeng Lu, Shan Ren, Yisi Liu, Xiaoxiao Wang, Sujun Zheng, Lina Ma, Zhenhuan Cao, Xinyue Chen   +10 more
doaj   +1 more source

Pediatric non alcoholic fatty liver disease: old and new concepts on development, progression, metabolic insight and potential treatment targets [PDF]

, 2013
Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease in children. NAFLD has emerged to be extremely prevalent, and predicted by obesity and male gender.
Giorgio V, Graziano F, Nobili V., Prono F   +3 more
core   +1 more source

PPARs and Liver Disease [PDF]

PPAR Research, 2013
This special issue of PPAR Research contains four interesting reviews and a research article examining the relevance of PPARs to liver diseases. Peroxisome proliferation-activated receptors (PPARs) are members of the nuclear hormone receptor superfamily and have been implicated in a variety of pathologic processes. PPARs require heterodimerization with
Yasuteru Kondo, Kenji Uno, Keigo Machida, Masanori Terajima   +3 more
openaire   +4 more sources

Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog [PDF]

, 2009
Alcohol synergistically enhances the progression of liver disease and the risk for liver cancer caused by hepatitis C virus (HCV). However, the molecular mechanism of this synergy remains unclear.
Asahina, Kinji, Deshaies, Raymond, Duan, Lewei, Dynnyk, Alla, Govindarajan, Sugantha, Lai, Michael M.-C., Liu, Helene Minyi, Machida, Keigo, Miyake, Kensuke, Mkrtchyan, Hasmik, Ou, Jing-hsiung James, Ray, Ratna, Seki, Ekihiro, Tsukamoto, Hidekazu   +13 more
core   +2 more sources

Endothelial dysfunction in adolescents and young adults with nonalcoholic liver disease [PDF]

, 2019
Nonalcoholic liver disease is a global public health problem that increases cardiovascular morbidity and mortality in these patients. This paper discusses endothelial dysfunction among patients (adolescents and young adults) with nonalcoholic liver ...
Donoiu, Ionuț, Istrătoaie, Octavian, Moise, Cristiana G, Mustafa, Edme R, Rogoveanu, Ion, Tudorașcu, Diana R, TÂRTEA, Georgică C   +6 more
core   +1 more source