Results 191 to 200 of about 1,230,040 (315)

Targeting magnesium homeostasis: a novel therapeutic strategy for liver diseases. [PDF]

Front Nutr
Ji L, Yu H, Wang R, Yan H, Yin X, Guo S, Wang R.   +6 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Correction: Fuzheng Huayu formula ameliorates chronic cholestatic liver injury by upregulating PPARa in mice

Chinese Medicine
Zheng Zhang, En-qi Tang, Chun-hui Li, Bi-bi Wang, Yue Liang, Jin-xin Lv, Gao-feng Chen, Wei Liu, Yong-ping Mu, Ping Liu, Jia-mei Chen   +10 more
doaj   +1 more source

Special Issue "Mechanistic and Prognostic Biomarkers in Liver Diseases". [PDF]

Livers
Jaeschke H, McGill MR.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Matrine in Liver Diseases: Mechanistic Insights and Therapeutic Potential. [PDF]

Drug Des Devel Ther
Wen W, Xia J, Liu G, Wang C.
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Large Language Models for Diagnosis and Prognosis of Chronic Liver Diseases: A Systematic Review. [PDF]

Health Sci Rep
Njei B, Al-Ajlouni YA, Ajayi A, Shahin F, Ta'ani OA, Boateng S, Ketwaroo G, Protiva P.   +7 more
europepmc   +1 more source

International Association for the Study of the Liver and the African Association for the Study of Liver Diseases ... meeting

, 2006
African Association for the Study of Liver Diseases, International Association for the Study of the Liver   +1 more
core  

EASL Clinical Practice Guidelines on genetic cholestatic liver diseases

Genetic cholestatic liver diseases are caused by (often rare) mutations in a multitude of different genes. While these diseases differ in pathobiology, clinical presentation and prognosis, they do have several commonalities due to their cholestatic ...
European Association for the Study of the Liver
core