Results 231 to 240 of about 301,775 (266)
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Gastroenterology Clinics of North America, 2019
All chronic liver disease can lead to liver fibrosis. Assessment of the severity of liver fibrosis is central to making treatment and management decisions. Liver biopsy, the gold standard for liver fibrosis assessment, is invasive and carries risks of complications and sampling errors.
Michelle, Lai, Nezam H, Afdhal
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All chronic liver disease can lead to liver fibrosis. Assessment of the severity of liver fibrosis is central to making treatment and management decisions. Liver biopsy, the gold standard for liver fibrosis assessment, is invasive and carries risks of complications and sampling errors.
Michelle, Lai, Nezam H, Afdhal
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Clinica Chimica Acta, 2012
Autotaxin (ATX) hydrolyzes lysophosphatidylcholine to produce lysophosphatidic acid (LPA), a multi-functional bioactive lipid mediator. ATX is a major determinant of LPA levels in the blood, and the pathophysiological functions of ATX are thought to be largely attributed to its ability to produce LPA.
Hitoshi, Ikeda, Yutaka, Yatomi
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Autotaxin (ATX) hydrolyzes lysophosphatidylcholine to produce lysophosphatidic acid (LPA), a multi-functional bioactive lipid mediator. ATX is a major determinant of LPA levels in the blood, and the pathophysiological functions of ATX are thought to be largely attributed to its ability to produce LPA.
Hitoshi, Ikeda, Yutaka, Yatomi
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Seminars in Liver Disease, 2017
AbstractLiver fibrosis is a common consequence of chronic liver injury and is a key determinant of liver-associated morbidity and mortality. Identification of new mechanisms of fibrosis, including disease-specific molecular drivers, remains relevant to reveal novel biomarkers and therapeutic targets.
Veronica, Massey +2 more
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AbstractLiver fibrosis is a common consequence of chronic liver injury and is a key determinant of liver-associated morbidity and mortality. Identification of new mechanisms of fibrosis, including disease-specific molecular drivers, remains relevant to reveal novel biomarkers and therapeutic targets.
Veronica, Massey +2 more
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Liver Fibrosis in Alcoholic Liver Disease
Seminars in Liver Disease, 2015Excessive alcohol consumption causes a wide spectrum of liver disease, ranging from simple steatosis to severe forms of liver injury such as steatohepatitis, liver fibrosis, cirrhosis, and liver cancer. Moreover, alcohol consumption also accelerates liver fibrosis in patients with other types of liver diseases such as viral hepatitis and nonalcoholic ...
Ramon, Bataller, Bin, Gao
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Liver fibrosis in paediatric liver diseases
Best Practice & Research Clinical Gastroenterology, 2011Numerous paediatric liver diseases from different origins may be complicated by development of liver fibrosis and progression to cirrhosis. Although fibrogenesis, which represents a major driving force for the development of liver fibrosis, has common tracts whatever the aetiology, liver fibrosis has different histopathological patterns in paediatric ...
Alisi A, de Vito R, Monti L, Nobili V.
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Journal of Gastroenterology and Hepatology, 2011
AbstractFibrosis prediction is an essential part of the assessment and management of patients with chronic liver disease. Blood‐based biomarkers offer a number of advantages over the traditional standard of fibrosis assessment of liver biopsy, including safety, cost‐savings and wide spread accessibility.
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AbstractFibrosis prediction is an essential part of the assessment and management of patients with chronic liver disease. Blood‐based biomarkers offer a number of advantages over the traditional standard of fibrosis assessment of liver biopsy, including safety, cost‐savings and wide spread accessibility.
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2013
Liver fibrosis is the final common pathway for almost all causes of chronic liver injury. Liver fibrosis is now known to be a dynamic process having significant potential for resolution. Therefore, fibrosis prediction is an essential part of the assessment and management of patients with chronic liver disease.
Ki Tae, Suk +3 more
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Liver fibrosis is the final common pathway for almost all causes of chronic liver injury. Liver fibrosis is now known to be a dynamic process having significant potential for resolution. Therefore, fibrosis prediction is an essential part of the assessment and management of patients with chronic liver disease.
Ki Tae, Suk +3 more
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Liver Disease in Cystic Fibrosis
Journal of Pediatric Gastroenterology and Nutrition, 2006ABSTRACTLiver involvement in Cystic Fibrosis (CF) is much less frequent than both pulmonary and pancreatic diseases that are present in 80‐90% of CF patients; liver disease (LD) affects only one third of CF patients, however, because of the decreasing mortality from extrahepatic causes, its recognition and management is becoming a relevant clinical ...
C. Colombo +3 more
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Genomics of Liver Fibrosis and Cirrhosis
Seminars in Liver Disease, 2007Hepatic fibrosis is the response to chronic injury from viral, toxic, metabolic, cholestatic, or autoimmune liver injury. However, only a minority of affected individuals develop advanced fibrosis or cirrhosis, suggesting that modifiers determine the individual risk. Aside from well-established progression factors including gender, duration of exposure
Osterreicher, Christoph H +2 more
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Expert Review of Gastroenterology & Hepatology, 2008
Prognosis and management of chronic liver diseases greatly depend on the amount and progression of liver fibrosis. Although liver biopsy is still considered as the gold standard to evaluate fibrosis in the liver, it is an invasive procedure, with rare but potentially life-threatening complications, and is prone to sampling errors.
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Prognosis and management of chronic liver diseases greatly depend on the amount and progression of liver fibrosis. Although liver biopsy is still considered as the gold standard to evaluate fibrosis in the liver, it is an invasive procedure, with rare but potentially life-threatening complications, and is prone to sampling errors.
openaire +2 more sources