Results 161 to 170 of about 2,212,278 (393)

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Hepatocellular Malignant Neoplasm, Not Otherwise Specified: A New Name in Liver Tumors: A Brief Narrative Review of Published Cases [PDF]

, 2021
Bita Geramizadeh, Razieh Foroughi, Alireza Shojazadeh   +2 more
openalex   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Conditional liver-specific expression of simian virus 40 T antigen leads to regulatable development of hepatic neoplasm in transgenic mice.

, 2002
Elanchezhiyan Manickan, Jujin Satoi, Timothy C. Wang, T. Jake Liang   +3 more
openalex   +1 more source

The establishment of the first ex vivo whole organ model for human liver neoplasms [PDF]

, 2020
Qiang Zhao, Jingjing Li, Caihui Zhu, Honghui Chen, Yihao Ma, Weixin Luo, Rongxing Xie, Yixi Zhang, Xiaobo Wang, Linhe Wang, Zhiheng Zhang, Zhiyong Guo, Xiaoshun He   +12 more
openalex   +1 more source

An extremely rare phenomenon of mucinous cystic neoplasm of the liver: spontaneous rupture [PDF]

, 2021
Xiaofeng Xu, Chuanhui Peng, Rongliang Tong, Miaoxia Dong, Junfang Deng   +4 more
openalex   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Yttrium-90 Radioembolization for Hepatic Metastases Secondary to Thymic Malignancies: A Case Report

JTO Clinical and Research Reports
The current guidelines for the treatment of extrathoracic metastases secondary to thymic neoplasms recommend chemotherapy. Thymic carcinomas are radiosensitive, and radiation therapy is recommended for intrathoracic masses and isolated metastases that ...
Gavin Yuan, BA, Elena N. Petre, MD, Etay Ziv, MD, PhD, Brett Marinelli, MD, Ken Zhao, MD, Vlasios Sotirchos, MD, Erica S. Alexander, MD   +6 more
doaj  

4MO A novel AI solution for auto-segmentation of multi-origin liver neoplasms [PDF]

, 2020
Akshayaa Vaidyanathan, Yousif Widaatalla, Abdalla Ibrahim, Fadila Zerka, Henry C. Woodruff, Ralph T. H. Leijenaar, Wim Vos, Seán Walsh, Philippe Lambin   +8 more
openalex   +1 more source