Results 131 to 140 of about 2,386,823 (356)

Anatomic versus non‐anatomic liver resection for hepatocellular carcinoma—A European multicentre cohort study in cirrhotic and non‐cirrhotic patients

open access: yesCancer Medicine
Background The incidence of hepatocellular carcinoma (HCC) is increasing in the western world over the past decades. As liver resection (LR) represents one of the most efficient treatment options, advantages of anatomic (ALR) versus non‐anatomic liver ...
Jasmin Zeindler   +9 more
doaj   +1 more source

METTL1‐Mediated M7G tRNA Modification Promotes Residual Liver Regeneration After Hepatectomy via Translational Control

open access: yesAdvanced Science, EarlyView.
METTL1 and its mediated m7G tRNA modification are significantly up‐regulated after partial hepatectomy (PHx). Overexpression of METTL1 improves the efficiency of liver regeneration after PHx, increases the proliferation of hepatocytes, and accelerates the recovery of liver function.
Manling Huang   +18 more
wiley   +1 more source

Splenectomy reduces shear stress and inflammation in liver endothelial cells during regeneration after partial hepatectomy in mice

open access: yesScientific Reports
Clinical and experimental findings indicate that splenectomy stimulates liver regeneration. The mechanisms of this effect are uncertain. This study aimed to assess the effect of splenectomy on the state of sinusoidal endothelial cells during liver ...
Andrey Elchaninov   +6 more
doaj   +1 more source

Efficiency of two-stage extensive resection interventions in the surgical treatment of patients with disseminated echinococcosis of the liver

open access: hybrid, 2023
A. O. Krasnov   +4 more
openalex   +2 more sources

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

open access: yesAdvanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li   +17 more
wiley   +1 more source

The Effects of FR167653 on Extended Liver Resection with Ischemia in Dogs

open access: diamond, 1998
Junya Kobayashi   +6 more
openalex   +2 more sources

Significance of Anatomic Resection for the Patients with Primary Solitary Hepatocellular Carcinoma Located on the Liver Surface [PDF]

open access: bronze, 2021
Daisuke Hokuto   +8 more
openalex   +1 more source

Amphiregulin and Epiregulin Confer Radioresistance in Esophageal Squamous Cell Carcinoma Through Oxidative Phosphorylation

open access: yesAdvanced Science, EarlyView.
Oxidative phosphorylation (OXPHOS) activity serves as a critical metabolic determinant of radiotherapy outcomes in esophageal squamous cell carcinoma (ESCC). The CEBPB/AREG/EREG axis drives radioresistance in ESCC by reprogramming OXPHOS. AREG and EREG function as predictive biomarkers for nCRT response and prognosis of ESCC patients.
Zhang Lin   +15 more
wiley   +1 more source

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