Results 161 to 170 of about 2,386,823 (356)

KRAS Withdrawal in Cholangiocarcinoma Leads to Immune Infiltration and Tumor Regression

Advanced Science, EarlyView.
Cholangiocarcinoma (CCA) driven by oncogenic KRAS depends on its continuous activation for tumor maintenance. Using a conditional KRAS model, the authors show that turning off KRAS triggers rapid tumor regression accompanied by immune cell infiltration and cytokine release. The findings uncover a KRAS–senescence–immune signaling axis and highlight KRAS
Youwei Qiao, Matthew F. Yee, Chaitanya N. Parikh, Boyang Ma, Yueying Cao, Yu‐Huan Shih, Joae Qiong Wu, Marcus Ruscetti, Shun‐Qing Liang, Wen Xue   +9 more
wiley   +1 more source

Feasibility of robotic liver resection compared with laparoscopic and open liver resection for hepatocellular carcinoma: a network meta-analysis. [PDF]

Int J Surg
Kim SH, Kim KH, Pinto-Marques H, Coelho JS.   +3 more
europepmc   +1 more source

Homoisoflavanone Delays Colorectal Cancer Progression via DNA Damage‐Induced Mitochondrial Apoptosis and Parthanatos‐Like Cell Death

Advanced Science, EarlyView.
Homoisoflavanone (HIF), a bioactive compound isolated from Polygonatum kingianum, selectively suppresses colorectal cancer progression by inducing DNA damage‐mediated mitochondrial apoptosis and parthanatos‐like cell death. HIF triggers mitochondrial dysfunction, including depolarized membrane potential, elevated ROS, and ATP depletion, while impairing
Hongjie Fan, Huzi Zhao, Pei Zhang, Pengfei Yu, Yunfei Ji, Gang Chen, Hongli Jin, Yanfang Liu, Jin Liu, Zhe‐Sheng Chen, Aiping Lyu, Xinmiao Liang, Yang Chen   +12 more
wiley   +1 more source

Erratum: Clinical efficacy of precision liver resection for primary liver cancer. [PDF]

Am J Transl Res
Zhang Y, Hu T, Wang Z, Yuan J.
europepmc   +1 more source

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

Advanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang, Juan Ye, Mitchell Sun, Samik Chakraborty, Alex Valenzuela, Shuran Chen, Qingfeng Xue, Wenyu Shi, Karel Pacak, Herui Wang, Zhengping Zhuang   +10 more
wiley   +1 more source

Preoperative predictors of unplanned conversion in laparoscopic liver resection: a multicenter cohort analysis. [PDF]

Front Oncol
Jiang Y, Yadav DK, Wang G, Jiang Z, Zhang S, Cheng G, Zhou X, Wang H, Li H, Hu Y, Hua Y.   +10 more
europepmc   +1 more source

Laparoscopic liver resection: the current status and the future.

Hepatobiliary surgery and nutrition, 2018
Xiujun Cai
semanticscholar   +1 more source

Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis

Advanced Science, EarlyView.
Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang, Mengqing Sun, Heng Dong, Xiaoting Zhang, Jingbo Zhang, Zhengguo Zhang, Mengjie Ni, Lina Li, Yunxin Pei, Xiaoyu Chen, Qian Li, Fangtian Bu, Jiacheng Huang, Liangyu Jiang, Zhuting Fang, Xuliang Chen, Jianxiang Chen, Yiting Qiao, Tian Xie   +18 more
wiley   +1 more source

The E-AHPBA-ESSO-Innsbruck consensus recommendations on peri- and postoperative management following liver resection. [PDF]

Br J Surg
Maier E, Stättner S, Carrion-Alvarez L, Di Martino M, Olthof P, Primavesi F, Sochorova D, van Laarhoven S, Balakrishnan A, Breitkopf R, Buis CI, Cipriani F, Erdmann J, Frampton A, Fuks D, Gilg S, Gulla A, Lancellotti F, Margreiter C, Melloul E, Oberkofler C, Petritsch S, Raab H, Rahbari NN, Rappold D, Reiberger T, Ruzzenente A, Sallinen V, Schaefer B, Schnitzbauer AA, Serrablo A, Soreide K, Sparrelid E, Starlinger P, Stavrou GA, Tinguely P, Aldrighetti L, Dasari BVM, Donadon M, Dopazo C, Gruenberger T, Jonas E, Malik H, Viganó L, Siriwardena AK, Maglione M.   +45 more
europepmc   +1 more source

The Role of TARE for Bridging and Downstaging of HCC Before Resection or Liver Transplant [PDF]

Abdullah Alshamrani, S K Cho, Namkee Oh, Jinsoo Rhu, Gyu-Seong Choi, Dong-Ho Hyun, Jongman KIM   +6 more
openalex   +1 more source