Results 241 to 250 of about 325,306 (358)

Reprogramming Tumor‐Associated Macrophages via Targeted NAT10 Inhibition to Enhance Colorectal Cancer Immunotherapy

Advanced Science, EarlyView.
This study presents the sono‐sensitive nanorobot Sono@NAT10, which targets NAT10 condensates to reprogram tumor‐associated macrophages in colorectal cancer. By reducing the acetylation level of SRSF2 protein and activating HDAC10, Sono@NAT10 promotes M1 polarization, suppresses tumor progression, and strengthens immunotherapy. The approach demonstrates
Jiahao Zhu, Benjie Xu, Rui Hu, Bo Yang, Peipei Shen, Yu Xu, Xiaojun Zhang, Danqi Qian, Gang Wu, Shengjun Ji, Yutian Zhao, Ke Gu   +11 more
wiley   +1 more source

Is liver resection necessary for T2 gallbladder cancer? [PDF]

Hepatobiliary Surg Nutr
Ituarte PHG, Singh G.
europepmc   +1 more source

THE CLINICAL SIGNIFICANCE OF SPLENECTOMY IN PATIENTS UNDERGOING HEPATIC RESECTION FOR HEPATOCELLULAR CARCINOMA WITH LIVER CIRRHOSIS

, 1998
Yasuaki Hirooka, Ichiro Konishi, Naoki Satoh, Yutaka Yamashiro, Yumi Yamaguchi, Tetsuya Kaneko, Takahumi HAYASHI, Kiyoaki Mizusawa, Nobuaki Kaibara, Ryuichi Hamazoe   +9 more
openalex   +2 more sources

A Multifunctional Molecular Probe for Multimodal Imaging‐Guided Potent Photothermal/Photodynamic Therapy of Endometriosis

Advanced Science, EarlyView.
The cRGD‐ILD molecular probe integrates clinically available components: a cRGD peptide (integrin αvβ3 targeting), ICG (for fluorescence/photoacoustic imaging and phototherapy), and Gd‐DTPA (MRI contrast). Utilizing small size and receptor targeting, it achieves selective lesion accumulation.
Qiyu Zhong, Shuguang Yang, Xiao Li, Zhuang Jin, Jianyu Ma, Zhouzhou Liao, Jinbo Li, Bo Li, Xintao Shuai, Shuqin Chen   +9 more
wiley   +1 more source

Self-Expanding metal stent placement for hepatic venous outflow obstruction following ex vivo liver resection and autotransplantation. [PDF]

Langenbecks Arch Surg
You X, Zuo B, Yang C, Liu T, Cheng D, Peng J, Li P, Hao J, Zhang Y.   +8 more
europepmc   +1 more source

A STUDY OF SURGICAL THERAPY FOR RECURRENCES AFTER RESECTION OF LIVER METASTASES FROM COLORECTAL CANCER

, 1999
Kenji MIZUKAMI, Tutomu KOH, Yuichi Arimoto, Y. Fukunaga, Katsuhiko Horii, Sinya TANIMURA, Mitsuharu Matsuyama, Osamu Yamazaki, Yasuhisa Fujimoto, Masayuki Higashino, Masahiro Okuno, Michio Sowa   +11 more
openalex   +2 more sources

NQO1/p65/CXCL12 Axis‐Recruited Tregs Mediate Resistance to Anti‐PD‐1 Plus Lenvatinib Therapy in PIVKA‐II‐Positive Hepatocellular Carcinoma

Advanced Science, EarlyView.
High PIVKA‐II expression in HCC correlates with resistance to anti‐PD‐1 plus lenvatinib, driven by an immunosuppressive TME. NQO1/p65/CXCL12 axis recruits Tregs to promote resistance to anti‐PD‐1 plus lenvatinib in HCC with high PIVKA‐II expression.
Biao Gao, Yafei Wang, Zhuoya Sun, Haowen Tang, Yinbiao Cao, Hao Jiang, Wenwen Zhang, Yinzhe Xu, Bingyang Hu, Zhe Liu, Guankun Mao, Xuerui Li, Junfeng Li, Tao Wan, Bing Liu, Xiao Zhao, Shunchang Jiao, Chonghui Li, Shichun Lu   +18 more
wiley   +1 more source

Oral carbohydrate intake before selective laparoscopic liver resection reduces insulin resistance and enhances recovery. [PDF]

Am J Transl Res
Li H, Zhao Y, Wang Y, Chen C.
europepmc   +1 more source

EFFECTS OF INTRAPORTAL PROSTAGLANDIN E1 ADMINISTRATION ON HEPATIC FUNCTION DURING AND AFTER CIRRHOTIC LIVER RESECTION IN PATIENTS WITH HEPATOCELLULAR CARCINOMA

, 1999
Yasuaki Hirooka, Kazunori Suzuki, Ichiro Konishi, Naoki Sato, Nobuaki Kaibara   +4 more
openalex   +2 more sources

Assessing the Nature of Human Brain‐Derived Extracellular Vesicles on Synaptic Activity Via the Development of an Air‐liquid Microfluidic Platform

Advanced Science, EarlyView.
This seminal study highlights the interwoven and tightly regulated functions of brain‐derived extracellular vesicles. Using microfluidics, proteomics, and AI‐based electric signal analyses of cortical brain explants, this work provides a useful resource dataset revealing the composition of human brain‐derived extracellular vesicles obtained from ...
Corentin Bernou, Yukiko Iwasaki, Willy Lutz, Glaucia Almeida, Emilie Béchard, François Delalande, Magali Rompais, Jules Bouget, Barbara Gorda, Chantal Cazevieille, Yonis Bare, Christine Carapito, Sophie Colomb, Gowrishankar Ganesh, Raphael Gaudin   +14 more
wiley   +1 more source