Results 171 to 180 of about 327,334 (304)

3D Printing for Neural Repair: Bridging the Gap in Regenerative Medicine

Advanced Materials, EarlyView.
This perspective article discusses how 3D bioprinting is advancing the development of neural tissue models and implants. It highlights recent progress in fabricating complex, multicellular neural constructs, examines current technical barriers, and outlines future applications in disease modeling, neurotoxicity testing, and regenerative therapies ...
Mitchell St Clair‐Glover, Zhilian Yue, Mirella Dottori   +2 more
wiley   +1 more source

Application of a single-cell-RNA-based biological-inspired graph neural network in diagnosis of primary liver tumors

Journal of Translational Medicine
Single-cell technology depicts integrated tumor profiles including both tumor cells and tumor microenvironments, which theoretically enables more robust diagnosis than traditional diagnostic standards based on only pathology.
Dao-Han Zhang, Chen Liang, Shu-Yang Hu, Xiao-Yong Huang, Lei Yu, Xian-Long Meng, Xiao-Jun Guo, Hai-Ying Zeng, Zhen Chen, Lv Zhang, Yan-Zi Pei, Mu Ye, Jia-Bin Cai, Pei-Xin Huang, Ying-Hong Shi, Ai-Wu Ke, Yi Chen, Yuan Ji, Yujiang Geno Shi, Jian Zhou, Jia Fan, Guo-Huan Yang, Qi-Man Sun, Guo-Ming Shi, Jia-Cheng Lu   +24 more
doaj   +1 more source

One‐Step Coordinated Multi‐Kinetic 4D Printing of Human Vascularized Cardiac Tissues with Selective Fast‐Shrinking Capillaries

Advanced Materials, EarlyView.
This study presents a novel 4D bioprinting technique for fabricating cardiac tissues with complex microvasculature. Unlike traditional 3D printing, it enables capillary‐scale structure formation via selective post‐printing shrinkage. This approach overcomes resolution limits of printing cell‐laden hydrogels, allowing the creation of functional ...
Ester Sapir Baruch, Roni Cohen, Eric Silberman, Michael Namestnikov, Itai Cabilly, Assaf Shapira, Tal Dvir   +6 more
wiley   +1 more source

Liver Transplantation to Provide Low-Density-Lipoprotein Receptors and Lower Plasma Cholesterol in a Child with Homozygous Familial Hypercholesterolemia [PDF]

, 1984
David W. Bilheimer, Joseph L. Goldstein, Scott M. Grundy, Thomas E. Starzl, Michael S. Brown   +4 more
openalex   +1 more source

Thermal Annealing Enhances Piezoelectricity and Regenerative Potential of PVDF‐TrFE Nanofiber Scaffolds

Advanced Materials Technologies, EarlyView.
Thermal annealing improves the structure, stiffness, and piezoelectric properties of poly(vinylidene flouride‐trifluoroethylene) (PVDF‐TrFE) nanofiber scaffolds. These annealed scaffolds promote Schwann cell proliferation and matrix remodeling in vitro and demonstrate in vivo biocompatibility.
Maksym Krutko, Holly M. Poling, Maulee Sheth, Supasek Kongsomros, Andrew E. Bryan, Manju Sharma, Akaljot Singh, Hasan A. Reza, Kathryn A. Wikenheiser‐Brokamp, Takanori Takebe, Michael A. Helmrath, Greg M. Harris, Leyla Esfandiari   +12 more
wiley   +1 more source

Microneedles From Shape‐Preserving Crosslinked Poly(Vinyl Alcohol) Hydrogels: Minimising Interference in Transdermal Proteomics

Advanced Materials Technologies, EarlyView.
Hydrogel‐forming microneedle patches are developed using shape‐preserving PVA‐PVP hydrogels, with and without chitosan, for minimally invasive transdermal protein biomarker sampling. The optimised patches enable efficient interstitial fluid uptake and proteomic analysis, while minimising interference.
Achmad Himawan, Robert Graham, Fabiana Volpe‐Zanutto, Huanhuan Li, Anjali K. Pandya, Andi Nur Aisyah, Rina Agustina, Juan L. Paris, Juan Dominguez‐Robles, Lalitkumar K. Vora, Andi D. Permana, Christopher J. Scott, Ryan F. Donnelly   +12 more
wiley   +1 more source

<i>&Delta;</i>⁴-Cholestenone Metabolism in Rat Liver Transplanted with Walker Carcinoma

, 1968
Tadashi Aizawa
openalex   +2 more sources

An Assessment of Orthotopic Liver Transplantation in Acute Liver Failure [PDF]

, 1984
Roger J. Williams, Alexander Gimson
openalex   +1 more source

Microphysiological Systems in Cancer Research: Advancing Immunotherapy through Tumor Microenvironment‐Integrated Organ‐On‐Chip Models

Advanced Therapeutics, EarlyView.
Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi, Francesco Noto, Jyothsna Vasudevan, Xavier Bisteau, Giulia Adriani, Andrea Pavesi   +5 more
wiley   +1 more source

Orthotopic Liver Transplantation for Alcoholic Cirrhosis [PDF]

, 1988
Thomas E. Starzl
openalex   +2 more sources