Results 241 to 250 of about 2,986,927 (385)
An Off‐the‐Shelf Artificial Proregenerative Macrophage for Pressure Ulcer Treatment
Artificial macrophages (artM) by encapsulating M2 lysates into biodegradable PLGA microspheres and coated with macrophage membrane, are engineered as new therapeutics against skin pressure ulcer. In mouse models, the artM exhibited robust tissue repair through cell recruitment and microenvironment modulation, showing great therapeutic potential for ...
Qi Su+12 more
wiley +1 more source
Effect of Pancreas Transplantation on Liver Carbohydrate Metabolism in Streptozotocin Diabetic Rats [PDF]
Idunn Brekke+2 more
openalex +1 more source
The splicing factor PTBP3 promotes COX11 exon skipping, allowing gastric cancer organoids to evade cuproptosis. Antisense oligonucleotide drugs targeting PTBP3‐mediated COX11 alternative splicing, in combination with copper ionophores, promote cuproptosis in organoids, thereby providing a therapeutic approach for gastric cancer peritoneal metastasis ...
Yajing Zhou+11 more
wiley +1 more source
EARLY INFECTIONS IN KIDNEY, HEART, AND LIVER TRANSPLANT RECIPIENTS ON CYCLOSPORINE
J. Stephen Dummer+3 more
openalex +1 more source
Low reproducibility and inefficient gene transfer hamper clinical manufacturing of chimeric antigen receptor regulatory T cells (CAR Tregs). Nanoneedle mediated electroporation generates primary human CAR Tregs under good manufacturing practice conditions with superior efficiency compared to viral transduction.
Ningjia Sun+12 more
wiley +1 more source
Glycolysis‐derived lactate activates nucleus pulposus cell ferroptosis via Histon H3K18la‐mediated ACSL4 transcription and ACSL4 lactylation and aggravate intervertebral disc degeneration. Inhibiting glycolysis via gene silencing or chemical intervention reduces the production of lactate and ameliorates ferroptosis activation and nucleus pulposus ...
Kaiqiang Sun+10 more
wiley +1 more source