Results 251 to 260 of about 357,211 (306)

NAD+‐Dependent Enzyme SIRT3 Limits Intestinal Epithelial Cell Functions Through NAD+ Synthesis Pathway in Colorectal Cancer

Advanced Science, EarlyView.
Microbiota‐derived quinolinic acid is used as an alternative source of replenishing the intracellular NAD+ pool induced by SIRT3 deficiency to regulate intestinal epithelial cell and T cell function, which has implications for targeting intestinal epithelial cells as an approach to the treatment of immune‐associated diseases, including colorectal ...
Ruiying Niu, Yingjie Dong, Jianghui Tong, Jingxuan Xia, Longhao Zhao, Zi Geng, Yingxin Lin, Jinghe Zhang, Xinyi Liu, Manqi Fang, Xi Jin, Yujing Bi, Guangwei Liu   +12 more
wiley   +1 more source

The emerging role of liver transplantation in metastatic colorectal cancer. [PDF]

Can Liver J
Rafael V, Yoshida EM, Chandok N.
europepmc   +1 more source

Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte‐Macrophage Crosstalk

Advanced Science, EarlyView.
Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan, Yuting Yong, Yuanshuai Li, Gaona Shi, Min Zhang, Lingfei Wan, Yue Zhao, Wenling Zhan, Yanli Lin, Qiaozhen Qin, Xupeng Chen, Yanli Ni, Haixu Chen, Wenzai Shi, Xiaomeng Guo, Juan Chen, Shuchen Liu, Youliang Wang, Bing Liu, Xinlong Yan   +19 more
wiley   +1 more source

The gut microbiota in liver transplantation recipients during the perioperative and postoperative recovery period. [PDF]

Front Microbiol
Bai Z, Wang Y, Li Y, Xu J, Lai Z.
europepmc   +1 more source

Targeting the Notch1‐YY1‐ICAM1 Signaling Axis Enhances the Efficacy of Immunotherapy in HCC by Activating CD8+ T‐Cell‐Driven Cancer Cell Pyroptosis

Advanced Science, EarlyView.
In hepatocellular carcinoma (HCC), aberrantly activated Notch1 signaling induces its target gene YY1, which impairs immunotherapy efficacy by suppressing tumor cell‐ICAM1‐driven T cell activation and the mediated pyroptosis of T cells against tumor cells.
Ke Zhu, Fa‐Peng Zhang, Chao Qin, Zhi‐Xiao Song, Cai‐Ni Yang, Shu‐Sheng Lin, Xian‐Huan Yu, Wen‐Rui Wu, Chao‐Qun Liu, Chao Liu, Lei‐Bo Xu   +10 more
wiley   +1 more source

Clinical outcomes of liver transplantation in Caroli syndrome: a retrospective analysis. [PDF]

Orphanet J Rare Dis
Hou F, Xiong HF, Liu Y, Zhao S, Zhang YZ, Kang Q, Liu JY, Wei L, Qu W, Zeng ZG, Zhu ZJ, Sun LY.   +11 more
europepmc   +1 more source

Machine learning-enhanced radiomics for predicting portal vein thrombectomy in liver transplantation. [PDF]

Hepatobiliary Surg Nutr
Luo XY, Liu ZK, Gao CH, Zheng SS, Yang Z.   +4 more
europepmc   +1 more source

Advanced imaging techniques at the crossroads of cholangiocarcinoma and liver transplantation: Can we bridge the gap? [PDF]

World J Gastrointest Surg
Lindner C.
europepmc   +1 more source

Advantages and future outlooks in the use of telemedicine in liver transplantation. [PDF]

World J Transplant
Zeppieri M.
europepmc   +1 more source

Evaluation of the stiffness of the transplanted liver and spleen in recipients after liver transplantation on shear wave elastography. [PDF]

Biomed Eng Online
Li J, Yang X, Zhang M, Ma L, Wang X, Wang X, Mao X, Li G.   +7 more
europepmc   +1 more source