Results 251 to 260 of about 3,082,572 (406)

Human hepatocyte transplantation for liver disease: current status and future perspectives

Pediatric Research, 2018
V. Iansante, R. Mitry, C. Filippi, E. Fitzpatrick, A. Dhawan   +4 more
semanticscholar   +1 more source

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Metabolic syndrome after liver transplantation: A silent threat to long-term success. [PDF]

World J Gastrointest Pharmacol Ther
Chan SY, Lee J, Karki P, Laryea M, Huang J, Lim N, Twohig P.   +6 more
europepmc   +1 more source

Functional decline in patients with cirrhosis awaiting liver transplantation: Results from the functional assessment in liver transplantation (FrAILT) study

Hepatology, 2016
J. Lai, J. Dodge, Ś. Sen, K. Covinsky, S. Feng   +4 more
semanticscholar   +1 more source

Piezoelectric Stimulation of Neural Cells: Exploring the Synergistic Potential of Hybrid Scaffolds for Enhanced Regeneration

Advanced Materials Interfaces, EarlyView.
Hybrid piezoelectric scaffolds offer a promising route for Central Nervous System regeneration by combining structural and electrical cues to support neural stem cell growth. This review highlights their potential to overcome current challenges in neural tissue engineering by exploring porous hybrid materials, their biological interactions, and ...
Heather F. Titterton, Chris R. Bowen, Hamideh Khanbareh   +2 more
wiley   +1 more source

Metabolic dysfunction-associated steatohepatitis is the leading indication for adult liver transplantation in Saudi Arabia. [PDF]

PLoS One
Alqahtani SA, AlMuhaidib S, Raptis DA, Al-Hamoudi WK, Reddy KR, Broering DC, Alghamdi SA, OTCE Collaborative.   +7 more
europepmc   +1 more source

3D‐Printed Functional Biphasic Scaffolds with Nanocomposites for Osteochondral Regeneration: A Step Toward Bioengineered Cartilage and Bone Integration

Advanced Materials Interfaces, EarlyView.
A biphasic scaffold comprised of polycaprolactone/laponite and methylsulfonylmethane (MSM)‐loaded polycaprolactone/chitosan is 3D‐printed to form an osteochondral interface. Strong interfacial adhesion between the bone and cartilage layers prevented interfacial separation.
Negin Khoshnood, Mostafa Shahrezaee, John P. Frampton, Mohammad Hossein Shahrezaee, Ali Zamanian   +4 more
wiley   +1 more source

Machine perfusion in liver transplantation: A step forward, but still on the runway. [PDF]

World J Gastroenterol
Kim SH.
europepmc   +1 more source

Directed Navigation of Magnetotactic Bacteria via Magnetotaxis in a 3D Vasculature‐On‐A‐Chip

Advanced Materials Technologies, EarlyView.
A perfusable vascular network is developed to investigate MTB at the single‐microorganism level. MTB is demonstrated to successfully align and navigate along the magnetic field inside the microvessels. Abstract Magnetotactic bacteria (MTB), inherently motile and self‐powered, are promising biorobotic candidates for targeted anti‐cancer drug delivery ...
Brianna Bradley, Yuji Nashimoto, Aldo Gonzalez‐Lopez, Takeshi Hori, Hirokazu Kaji, Peter L. Davies, Carlos Escobedo   +6 more
wiley   +1 more source

Advantages and future outlooks in the use of telemedicine in liver transplantation. [PDF]

World J Transplant
Zeppieri M.
europepmc   +1 more source