Results 171 to 180 of about 97,066 (261)

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli   +5 more
wiley   +1 more source

Urbanization and food transition in the Brazilian Amazon: From wild to domesticated meat

open access: yesPeople and Nature, EarlyView.
Abstract Urbanization is expected to influence food transitions, resulting in a shift from wild foods to more domesticated foods. Concomitantly, food insecurity and urban demand for natural resources, including wildlife, are expected to increase overall, even when the per capita consumption is expected to decrease.
Willandia A. Chaves   +7 more
wiley   +1 more source

The importance of wild meat and freshwater fish for children's nutritional intake in the Congo Basin

open access: yesPeople and Nature, EarlyView.
Abstract Wild meat and freshwater fish are widely consumed in the Congo Basin, but in some areas, they are at risk of disappearing due to unsustainable hunting and fishing and changes in their habitat. Wild meat is also at risk of being eliminated from local diets due to potential policy changes such as wild meat bans.
Amy Ickowitz   +6 more
wiley   +1 more source

How uneven access shapes the socio‐economic and environmental potential of game meat value chains: The case of legal game meat in Zambia

open access: yesPeople and Nature, EarlyView.
Abstract Game meat contributes to human nutrition, food security and sociocultural practices around the world. Game meat also comes with risks, including overharvesting and zoonotic and food‐borne disease. These may be pronounced where game meat travels along complex value chains from rural to urban areas.
Brock Bersaglio   +5 more
wiley   +1 more source

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