Results 111 to 120 of about 4,166,240 (311)

Made in China: The Sweatshop Behind the Bratz [PDF]

open access: yes, 2006
The report describes living and working conditions at the Hua Tai 4k factory in Shenzhen City, China. It is part of the large Hua Cheng group and supplies Bratz dolls mostly for California-based MGA Entertainment ...
China Labor Watch
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Which Sámi? Sámi inclusion criteria in population-based studies of Sámi health and living conditions in Norway – an exploratory study exemplified with data from the SAMINOR study

open access: yesInternational Journal of Circumpolar Health, 2013
Background. In a situation where national censuses do not record information on ethnicity, studies of the indigenous Sámi people's health and living conditions tend to use varying Sámi inclusion criteria and categorizations ...
Torunn Pettersen, Magritt Brustad
doaj   +1 more source

Life Sustains Life 1. Value: Social and Ecological [PDF]

open access: yes
I would like to address the question of social and ecological value by bringing two approaches to this question into conversation with one another and show their connections. The two approaches are those of Jonathan Schell and Akeel Bilgrami.
Tully, James
core  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Ageing in Norwegian Rural and Urban Communities

open access: yesEuropean Countryside, 2018
This paper, based on data from two recent national surveys of the residents of municipalities in Norway, compares rural and urban elderly people’s degree of satisfaction with locally available services and their reported involvement with others in the ...
Blekesaune Arild, Haugen Marit S.
doaj   +1 more source

Effect of marital status on death rates. Part 2: Transient mortality spikes

open access: yes, 2015
We examine what happens in a population when it experiences an abrupt change in surrounding conditions. Several cases of such "abrupt transitions" for both physical and living social systems are analyzed from which it can be seen that all share a common ...
Richmond, Peter, Roehner, Bertrand M.
core   +2 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

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