Results 111 to 120 of about 4,165,678 (306)

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Life Sustains Life 1. Value: Social and Ecological [PDF]

open access: yes
I would like to address the question of social and ecological value by bringing two approaches to this question into conversation with one another and show their connections. The two approaches are those of Jonathan Schell and Akeel Bilgrami.
Tully, James
core  

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

[Cholera and living conditions, Brazil].

open access: yesRevista de saude publica, 2000
INTRODUCTION: Factors associated with precarious living and environmental conditions are frequently cited as major obstacles for the control of cholera outbreaks and epidemics. The purposes of the study are to evaluate the contribution of factors associated with the population living conditions and correlate the environmental problems with the onset of
Gerolomo, Moacir, Penna, Maria LF
openaire   +2 more sources

Childhood Peer Status and the Clustering of Adverse Living Conditions in Adulthood [PDF]

open access: yes
Within the context of the school class, children attain a social position in the peer hierarchy to which varying amounts of status are attached. Several studies have shown that children’s peer status is associated with a wide range of social and health ...
Almquist, Ylva B., Brännström, Lars
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Internal migration and household living conditions in Ethiopia

open access: yesDemographic Research, 2006
Using the 1998 Migration, Gender and Health Survey in Five Regions of Ethiopia, and multivariate regression techniques, this paper examines the relationship between internal migration and household living conditions. The analysis finds significant living
Blessing Uchenna Mberu
doaj  

Economic development of pakistan_a brief review [PDF]

open access: yes
WHAT IS ECONOMIC DEVELOPMENT ? Economic development means sustainable qualitative changes in the living conditions of general public in a country over a long period of time. Living condition means economic wellbeing not only in material sense but also in
shazia kazmi
core  

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

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